PMID- 25100939
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20140807
LR  - 20211021
IS  - 1662-4548 (Print)
IS  - 1662-453X (Electronic)
IS  - 1662-453X (Linking)
VI  - 8
DP  - 2014
TI  - Fluorescent visualization of oxytocin in the hypothalamo-neurohypophysial system.
PG  - 213
LID - 10.3389/fnins.2014.00213 [doi]
LID - 213
AB  - Oxytocin (OXT) is well known for its ability to the milk ejection reflex and 
      uterine contraction. It is also involved in several other behaviors, such as 
      anti-nociception, anxiety, feeding, social recognition, and stress responses. OXT 
      is synthesized in the magnocellular neurosecretory cells (MNCs) in the 
      hypothalamic paraventricular (PVN) and the supraoptic nuclei (SON) that terminate 
      their axons in the posterior pituitary (PP). We generated transgenic rats that 
      express the OXT and fluorescent protein fusion gene in order to visualize OXT in 
      the hypothalamo-neurohypophysial system (HNS). In these transgenic rats, 
      fluorescent proteins were observed in the MNCs and axon terminals in the PP. This 
      transgenic rat is a new tool to study the physiological role of OXT in the HNS.
FAU - Hashimoto, Hirofumi
AU  - Hashimoto H
AD  - Department of Physiology, School of Medicine, University of Occupational and 
      Environmental Health Kitakyushu, Japan.
FAU - Matsuura, Takanori
AU  - Matsuura T
AD  - Department of Physiology, School of Medicine, University of Occupational and 
      Environmental Health Kitakyushu, Japan.
FAU - Ueta, Yoichi
AU  - Ueta Y
AD  - Department of Physiology, School of Medicine, University of Occupational and 
      Environmental Health Kitakyushu, Japan.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20140723
PL  - Switzerland
TA  - Front Neurosci
JT  - Frontiers in neuroscience
JID - 101478481
PMC - PMC4107947
OTO - NOTNLM
OT  - CCK
OT  - c-fos
OT  - double transgenic rat
OT  - mRFP1
OT  - paraventricular nucleus
OT  - posterior pituitary
OT  - supraoptic nucleus
EDAT- 2014/08/08 06:00
MHDA- 2014/08/08 06:01
PMCR- 2014/01/01
CRDT- 2014/08/08 06:00
PHST- 2014/04/30 00:00 [received]
PHST- 2014/07/02 00:00 [accepted]
PHST- 2014/08/08 06:00 [entrez]
PHST- 2014/08/08 06:00 [pubmed]
PHST- 2014/08/08 06:01 [medline]
PHST- 2014/01/01 00:00 [pmc-release]
AID - 10.3389/fnins.2014.00213 [doi]
PST - epublish
SO  - Front Neurosci. 2014 Jul 23;8:213. doi: 10.3389/fnins.2014.00213. eCollection 
      2014.