PMID- 25104808
OWN - NLM
STAT- MEDLINE
DCOM- 20150910
LR  - 20161125
IS  - 2047-2412 (Electronic)
IS  - 2047-2404 (Linking)
VI  - 15
IP  - 12
DP  - 2014 Dec
TI  - Prognostic value of pulmonary vascular resistance estimated by cardiac magnetic 
      resonance in patients with chronic heart failure.
PG  - 1391-9
LID - 10.1093/ehjci/jeu147 [doi]
AB  - AIMS: Pulmonary arterial hypertension is known to be related to worse prognosis 
      in patients with heart failure (HF). Quantification of pulmonary vascular 
      resistance (PVR) still requires invasive right heart catheterization. Recent 
      studies have shown an accurate method for non-invasive estimation of PVR by 
      cardiac magnetic resonance (CMR). Our aim was to evaluate the prognostic value of 
      PVR calculated by CMR in patients with congestive HF. METHODS AND RESULTS: We 
      calculated PVR by CMR in 132 patients [age 65.6 +/- 13.1 years, left ventricular 
      ejection fraction (LVEF) 35.1 +/- 16.4%, ischaemic aetiology 40%] recently admitted 
      for decompensated HF and derived to our cardiac imaging unit for diagnosis. 
      Patients with cardiac events (readmission for HF or all-cause death) had higher 
      values of PVR [6.77 +/- 1.9 vs. 4.1 +/- 1.6 Wood units (Wu), P < 0.001] during 
      follow-up [mean 10.3 (1-31) months]. In multivariable Cox regression analysis, 
      only a PVR >/=5.2 Wu [hazard ratio (HR) 4.27; 95% confidence interval (CI) 
      1.75-10.42; P < 0.001) and the presence of late gadolinium enhancement (LGE) on 
      CMR (HR 2.24; 95% CI 1.03-4.86; P = 0.04) were independent predictors for adverse 
      events at follow-up. CONCLUSION: Non-invasive estimation of PVR by CMR might be 
      useful for risk stratification of patients with chronic HF, irrespective of 
      aetiology or LVEF.
CI  - Published on behalf of the European Society of Cardiology. All rights reserved. (c) 
      The Author 2014. For permissions please email: journals.permissions@oup.com.
FAU - Fabregat-Andres, Oscar
AU  - Fabregat-Andres O
AD  - Cardiology Department, Consorcio Hospital General Universitario de Valencia, 
      Valencia, Spain Research Foundation, Hospital General Universitario, Valencia, 
      Spain osfabregat@gmail.com.
FAU - Estornell-Erill, Jordi
AU  - Estornell-Erill J
AD  - Cardiac Imaging Unit, ERESA, Valencia, Spain.
FAU - Ridocci-Soriano, Francisco
AU  - Ridocci-Soriano F
AD  - Cardiology Department, Consorcio Hospital General Universitario de Valencia, 
      Valencia, Spain Department of Medicine, Universitat de Valencia, Valencia, Spain.
FAU - Garcia-Gonzalez, Pilar
AU  - Garcia-Gonzalez P
AD  - Cardiology Department, Consorcio Hospital General Universitario de Valencia, 
      Valencia, Spain.
FAU - Bochard-Villanueva, Bruno
AU  - Bochard-Villanueva B
AD  - Cardiology Department, Consorcio Hospital General Universitario de Valencia, 
      Valencia, Spain.
FAU - Cubillos-Arango, Andres
AU  - Cubillos-Arango A
AD  - Cardiology Department, Consorcio Hospital General Universitario de Valencia, 
      Valencia, Spain.
FAU - Espriella-Juan, Rafael de la
AU  - Espriella-Juan Rde L
AD  - Cardiology Department, Consorcio Hospital General Universitario de Valencia, 
      Valencia, Spain.
FAU - Facila, Lorenzo
AU  - Facila L
AD  - Cardiology Department, Consorcio Hospital General Universitario de Valencia, 
      Valencia, Spain.
FAU - Morell, Salvador
AU  - Morell S
AD  - Cardiology Department, Consorcio Hospital General Universitario de Valencia, 
      Valencia, Spain.
FAU - Cortijo, Julio
AU  - Cortijo J
AD  - Research Foundation, Hospital General Universitario, Valencia, Spain Department 
      of Pharmacology, Universitat de Valencia, Valencia, Spain.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20140807
PL  - England
TA  - Eur Heart J Cardiovasc Imaging
JT  - European heart journal. Cardiovascular Imaging
JID - 101573788
SB  - IM
MH  - Aged
MH  - Chronic Disease
MH  - Coronary Angiography/methods
MH  - Echocardiography/methods
MH  - Female
MH  - Follow-Up Studies
MH  - Heart Failure/*diagnosis/diagnostic imaging/*mortality
MH  - Humans
MH  - Kaplan-Meier Estimate
MH  - Magnetic Resonance Imaging, Cine/*methods
MH  - Male
MH  - Middle Aged
MH  - Predictive Value of Tests
MH  - Prognosis
MH  - Prospective Studies
MH  - Risk Factors
MH  - Sensitivity and Specificity
MH  - Stroke Volume
MH  - *Vascular Resistance
MH  - Ventricular Function, Left
OTO - NOTNLM
OT  - Cardiac magnetic resonance
OT  - Heart failure
OT  - Non-invasive estimation
OT  - Prognosis
OT  - Pulmonary hypertension
OT  - Pulmonary vascular resistances
EDAT- 2014/08/12 06:00
MHDA- 2015/09/12 06:00
CRDT- 2014/08/09 06:00
PHST- 2014/08/09 06:00 [entrez]
PHST- 2014/08/12 06:00 [pubmed]
PHST- 2015/09/12 06:00 [medline]
AID - jeu147 [pii]
AID - 10.1093/ehjci/jeu147 [doi]
PST - ppublish
SO  - Eur Heart J Cardiovasc Imaging. 2014 Dec;15(12):1391-9. doi: 
      10.1093/ehjci/jeu147. Epub 2014 Aug 7.