PMID- 25105215 OWN - NLM STAT- MEDLINE DCOM- 20150330 LR - 20211021 IS - 1360-0451 (Electronic) IS - 0954-0121 (Print) IS - 0954-0121 (Linking) VI - 27 IP - 1 DP - 2015 TI - Depression and social functioning among HIV-infected and uninfected persons in South Africa. PG - 41-6 LID - 10.1080/09540121.2014.946383 [doi] AB - Depression and other health problems are common co-morbidities among persons living with human immunodeficiency virus infection/acquired immunodeficiency syndrome (HIV/AIDS). The aim of this study was to investigate depression, health status, and substance use in relation to HIV-infected and uninfected individuals in South Africa. Using a cross-sectional case-control design, we compared depression, physical health, mental health, problem alcohol use, and tobacco use in a sample of HIV-infected (N = 143) and HIV-uninfected (N = 199) respondents who had known their HIV status for two months. We found that depression was higher, and physical health and mental health were lower in HIV-positive than HIV-negative individuals. Poor physical health also moderated the effect of HIV infection on depression; HIV-positive individuals were significantly more depressed than HIV-negative controls, but only when general physical health was also poor. We did not find an association between alcohol or tobacco use and HIV status. These results suggest the importance of incorporating the management of psychological health in the treatment of HIV. FAU - Peltzer, Karl AU - Peltzer K AD - a HIV/STIs and TB Research Programme , Human Sciences Research Council , Pretoria , South Africa. FAU - Szrek, Helena AU - Szrek H FAU - Ramlagan, Shandir AU - Ramlagan S FAU - Leite, Rui AU - Leite R FAU - Chao, Li-Wei AU - Chao LW LA - eng GR - P30 AG012836/AG/NIA NIH HHS/United States GR - P30AG12836/AG/NIA NIH HHS/United States PT - Journal Article PT - Research Support, N.I.H., Extramural PT - Research Support, Non-U.S. Gov't DEP - 20140808 PL - England TA - AIDS Care JT - AIDS care JID - 8915313 SB - IM MH - Adolescent MH - Adult MH - Case-Control Studies MH - Cross-Sectional Studies MH - Depression/*complications MH - Female MH - HIV Infections/complications/*psychology MH - Humans MH - Male MH - Middle Aged MH - *Social Behavior MH - South Africa PMC - PMC4221564 MID - NIHMS616078 OTO - NOTNLM OT - HIV status OT - South Africa OT - co-morbidity OT - depression OT - mental health OT - physical health EDAT- 2014/08/12 06:00 MHDA- 2015/03/31 06:00 PMCR- 2016/01/01 CRDT- 2014/08/09 06:00 PHST- 2014/08/09 06:00 [entrez] PHST- 2014/08/12 06:00 [pubmed] PHST- 2015/03/31 06:00 [medline] PHST- 2016/01/01 00:00 [pmc-release] AID - 10.1080/09540121.2014.946383 [doi] PST - ppublish SO - AIDS Care. 2015;27(1):41-6. doi: 10.1080/09540121.2014.946383. Epub 2014 Aug 8.