PMID- 25107452 OWN - NLM STAT- MEDLINE DCOM- 20151019 LR - 20191112 IS - 2212-4063 (Electronic) IS - 1871-529X (Linking) VI - 14 IP - 2 DP - 2014 TI - Phospholipid transfer protein in diabetes, metabolic syndrome and obesity. PG - 149-53 AB - It has been reported that phospholipid transfer protein (PLTP) is an independent risk factor for human coronary artery disease. And metabolic tissues are important contributors to the systemic pools of PLTP protein. Consistently, PLTP mass and activity have been found to be elevated in the plasma of type 2 diabetes mellitus (T2DM) and obese patients. In this review, we summarized the recent progresses made in the PLTP research field and focused on the complexity of the implication of PLTP in obesity, insulin resistance and T2DM. FAU - Qin, Shucun AU - Qin S FAU - Song, Guohua AU - Song G FAU - Yu, Yang AU - Yu Y AD - Key Laboratory of Atherosclerosis in Universities of Shandong and Institute of Atherosclerosis, Taishan Medical University, Taian, China, 271000. shucunqin@hotmail.com. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Review PL - United Arab Emirates TA - Cardiovasc Hematol Disord Drug Targets JT - Cardiovascular & hematological disorders drug targets JID - 101269160 RN - 0 (Insulin) RN - 0 (Phospholipid Transfer Proteins) SB - IM MH - Animals MH - Diabetes Mellitus, Type 2/*metabolism MH - Humans MH - Insulin/metabolism MH - Insulin Resistance MH - Metabolic Syndrome/*metabolism MH - Obesity/*metabolism MH - Phospholipid Transfer Proteins/*metabolism EDAT- 2014/08/12 06:00 MHDA- 2015/10/20 06:00 CRDT- 2014/08/10 06:00 PHST- 2014/01/17 00:00 [received] PHST- 2014/04/27 00:00 [revised] PHST- 2014/04/28 00:00 [accepted] PHST- 2014/08/10 06:00 [entrez] PHST- 2014/08/12 06:00 [pubmed] PHST- 2015/10/20 06:00 [medline] AID - CHDDT-61686 [pii] AID - 10.2174/1871529x1402140807144435 [doi] PST - ppublish SO - Cardiovasc Hematol Disord Drug Targets. 2014;14(2):149-53. doi: 10.2174/1871529x1402140807144435.