PMID- 25110679
OWN - NLM
STAT- MEDLINE
DCOM- 20150331
LR  - 20220408
IS  - 2314-6141 (Electronic)
IS  - 2314-6133 (Print)
VI  - 2014
DP  - 2014
TI  - Evaluation of macular retinal ganglion cell-inner plexiform layer thickness after 
      vitrectomy with internal limiting membrane peeling for idiopathic macular holes.
PG  - 458631
LID - 10.1155/2014/458631 [doi]
LID - 458631
AB  - PURPOSE: To evaluate macular retinal ganglion cell-inner plexiform layer (GCIPL) 
      thickness changes after Brilliant Blue G-assisted internal limiting membrane 
      peeling for idiopathic macular hole repair using a high-resolution 
      spectral-domain optical coherence tomography (SD-OCT). METHODS: 32 eyes from 32 
      patients with idiopathic macular holes who underwent vitrectomy with internal 
      limiting membrane peeling between January 2011 and July 2012 were retrospectively 
      analyzed. GCIPL thickness was measured before surgery, and at one month and at 
      six months after surgery. Values obtained from automated and semimanual SD-OCT 
      segmentation analysis were compared (Cirrus HD-OCT, Carl Zeiss Meditec, Dublin, 
      CA). RESULTS: No significant differences were found between average GCIPL 
      thickness values between preoperative and postoperative analysis. However, 
      statistical significant differences were found in GCIPL thickness at the temporal 
      macular quadrants at six months after surgery. Quality measurement analysis 
      performed by automated segmentation revealed a significant number of segmentation 
      errors. Semimanual segmentation slightly improved the quality of the results. 
      CONCLUSION: SD-OCT analysis of GCIPL thickness found a significant reduction at 
      the temporal macular quadrants at 6 months after Brilliant Blue G-assisted 
      internal limiting membrane peeling for idiopathic macular hole.
FAU - Sabater, Alfonso L
AU  - Sabater AL
AUID- ORCID: 0000-0001-6383-2558
AD  - Department of Ophthalmology, Clinica Universidad de Navarra, 31008 Pamplona, 
      Spain.
FAU - Velazquez-Villoria, Alvaro
AU  - Velazquez-Villoria A
AD  - Department of Ophthalmology, Clinica Universidad de Navarra, 31008 Pamplona, 
      Spain.
FAU - Zapata, Miguel A
AU  - Zapata MA
AD  - Department of Ophthalmology, Hospital Universitario Vall d'Hebron, 08035 
      Barcelona, Spain ; Red Tematica de Investigacion Cooperativa en Oftalmologia 
      (RETICS-Oftared RD12/0034), Instituto de Salud Carlos III, Madrid, Spain.
FAU - Figueroa, Marta S
AU  - Figueroa MS
AD  - Red Tematica de Investigacion Cooperativa en Oftalmologia (RETICS-Oftared 
      RD12/0034), Instituto de Salud Carlos III, Madrid, Spain ; Department of 
      Ophthalmology, Hospital Universitario Ramon y Cajal, 28034 Madrid, Spain.
FAU - Suarez-Leoz, Marta
AU  - Suarez-Leoz M
AD  - Clinica Oftalmologica Suarez Leoz, 28010 Madrid, Spain.
FAU - Arrevola, Luis
AU  - Arrevola L
AD  - Clinica Baviera, 28046 Madrid, Spain.
FAU - Teijeiro, Maria-Angeles
AU  - Teijeiro MA
AD  - Clinica Baviera, 28046 Madrid, Spain.
FAU - Garcia-Layana, Alfredo
AU  - Garcia-Layana A
AD  - Department of Ophthalmology, Clinica Universidad de Navarra, 31008 Pamplona, 
      Spain ; Red Tematica de Investigacion Cooperativa en Oftalmologia (RETICS-Oftared 
      RD12/0034), Instituto de Salud Carlos III, Madrid, Spain.
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
PT  - Observational Study
DEP - 20140707
PL  - United States
TA  - Biomed Res Int
JT  - BioMed research international
JID - 101600173
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Demography
MH  - Epiretinal Membrane/pathology/*surgery
MH  - Female
MH  - Humans
MH  - Macula Lutea/*pathology/*surgery
MH  - Male
MH  - Middle Aged
MH  - Postoperative Care
MH  - Preoperative Care
MH  - Retinal Ganglion Cells/*pathology
MH  - Retinal Perforations/*pathology/*surgery
MH  - Tomography, Optical Coherence
MH  - *Vitrectomy
PMC - PMC4109220
EDAT- 2014/08/12 06:00
MHDA- 2015/04/01 06:00
PMCR- 2014/07/07
CRDT- 2014/08/12 06:00
PHST- 2014/05/09 00:00 [received]
PHST- 2014/06/13 00:00 [accepted]
PHST- 2014/08/12 06:00 [entrez]
PHST- 2014/08/12 06:00 [pubmed]
PHST- 2015/04/01 06:00 [medline]
PHST- 2014/07/07 00:00 [pmc-release]
AID - 10.1155/2014/458631 [doi]
PST - ppublish
SO  - Biomed Res Int. 2014;2014:458631. doi: 10.1155/2014/458631. Epub 2014 Jul 7.