PMID- 25115538
OWN - NLM
STAT- MEDLINE
DCOM- 20150723
LR  - 20220309
IS  - 1423-0267 (Electronic)
IS  - 0030-3755 (Linking)
VI  - 232
IP  - 3
DP  - 2014
TI  - Reproducibility and repeatability of ganglion cell-inner plexiform layer 
      thickness measurements in healthy subjects.
PG  - 163-9
LID - 10.1159/000362177 [doi]
AB  - PURPOSE: To assess the reproducibility and repeatability of macular ganglion 
      cell-inner plexiform layer (GC-IPL) thickness measurements in healthy subjects. 
      PROCEDURES: In this observational study, 60 healthy eyes were subjected to 
      macular GC-IPL thickness measurements by means of Cirrus high-definition optical 
      coherence tomography (Cirrus version 6.0; Carl Zeiss Meditec, Dublin, Calif., 
      USA) by two examiners in two sessions. Average, minimum and 6 sectoral GC-IPL 
      thicknesses were measured. Inter- and intraobserver reproducibility was tested 
      and analyzed by means of the concordance correlation coefficient (CCC). The 
      repeatability of measurements was assessed by the coefficient of repeatability 
      (CR). RESULTS: Mean age (+/-SD) was 29.63 (+/-5.1) years. The CRs for average GC-IPL 
      thickness were 2.1 and 2.2 microm for the first and the second operator, 
      respectively. Inter- and intraobserver CCCs ranged from 0.91 (95% CI: 0.89-0.93) 
      to 0.98 (95% CI: 0.96-0.99) and from 0.92 (95% CI: 0.88-0.94) to 0.98 (95% CI: 
      0.97-0.99), respectively. CONCLUSIONS: GC-IPL thickness measurements in young 
      healthy subjects showed excellent reproducibility and repeatability, especially 
      for average and sectoral GC-IPL thickness measurements.
CI  - 2014 S. Karger AG, Basel
FAU - Carpineto, Paolo
AU  - Carpineto P
AD  - Ophthalmology Clinic, University 'G. d'Annunzio' Chieti-Pescara, Chieti, Italy.
FAU - Aharrh-Gnama, Agbeanda
AU  - Aharrh-Gnama A
FAU - Ciciarelli, Vincenzo
AU  - Ciciarelli V
FAU - Mastropasqua, Alessandra
AU  - Mastropasqua A
FAU - Di Antonio, Luca
AU  - Di Antonio L
FAU - Toto, Lisa
AU  - Toto L
LA  - eng
PT  - Journal Article
PT  - Observational Study
DEP - 20140808
PL  - Switzerland
TA  - Ophthalmologica
JT  - Ophthalmologica. Journal international d'ophtalmologie. International journal of 
      ophthalmology. Zeitschrift fur Augenheilkunde
JID - 0054655
SB  - IM
MH  - Adult
MH  - Female
MH  - Gonioscopy
MH  - Healthy Volunteers
MH  - Humans
MH  - Intraocular Pressure/physiology
MH  - Male
MH  - Middle Aged
MH  - Observer Variation
MH  - Organ Size
MH  - Prospective Studies
MH  - Reproducibility of Results
MH  - Retina/anatomy & histology
MH  - Retinal Ganglion Cells/*cytology
MH  - Retinal Neurons/*cytology
MH  - Tomography, Optical Coherence
MH  - Visual Acuity/physiology
MH  - Young Adult
EDAT- 2014/08/15 06:00
MHDA- 2015/07/24 06:00
CRDT- 2014/08/14 06:00
PHST- 2013/11/18 00:00 [received]
PHST- 2014/03/07 00:00 [accepted]
PHST- 2014/08/14 06:00 [entrez]
PHST- 2014/08/15 06:00 [pubmed]
PHST- 2015/07/24 06:00 [medline]
AID - 000362177 [pii]
AID - 10.1159/000362177 [doi]
PST - ppublish
SO  - Ophthalmologica. 2014;232(3):163-9. doi: 10.1159/000362177. Epub 2014 Aug 8.