PMID- 25118262
OWN - NLM
STAT- MEDLINE
DCOM- 20141105
LR  - 20140909
IS  - 1552-5783 (Electronic)
IS  - 0146-0404 (Linking)
VI  - 55
IP  - 9
DP  - 2014 Aug 12
TI  - Posterior pole asymmetry analyses of retinal thickness of upper and lower sectors 
      and their association with peak retinal nerve fiber layer thickness in healthy 
      young eyes.
PG  - 5673-8
LID - 10.1167/iovs.13-13828 [doi]
AB  - PURPOSE: To determine the symmetry of the retinal thicknesses (RT) between the 32 
      pairs of superior and inferior sectors by posterior pole asymmetrical analysis 
      (PPAA) of the spectral-domain optical coherence tomographic (SD-OCT) images in 
      healthy eyes. In addition, to determine their association with the position of 
      the peak retinal nerve fiber layer (RNFL) thickness. METHODS: A prospective, 
      observational, cross-sectional study of 64 right eyes. The Spectralis SD-OCT was 
      used to obtain the images, and the PPAA determined the RT of the 64 cells within 
      the central 24 degrees  area. The program also compared the thicknesses of corresponding 
      cells across the fovea-disc axis. Circular scans were used to measure the supra- 
      and infratemporal RNFL peak angle differences (PADs). The relationships between 
      the RT of the corresponding cells and the relationship between the differences of 
      the RT of the corresponding cells and PAD were investigated by linear regression 
      analysis. RESULTS: The mean differences between the RT of corresponding cells 
      ranged from 3.1 to 23.2 mum. The RT of all upper cells were significantly 
      correlated with the RT of the corresponding lower cells (R = 0.45-0.97, P < 
      0.001). The coefficients of correlation between the corresponding pairs of 
      central- and temporal-macular cells were higher than that of the peripheral and 
      nasal-macular cells. The differences of the pairs of nasal-macular cells RT were 
      significantly correlated with the PAD. CONCLUSIONS: The symmetry of the RT 
      between the upper and lower cells was high in the central and temporal-macular 
      areas but not in the peripheral and nasal-macular areas. (www.umin.ac.jp/ctr 
      number, UMIN000006040.).
CI  - Copyright 2014 The Association for Research in Vision and Ophthalmology, Inc.
FAU - Yamashita, Takehiro
AU  - Yamashita T
AD  - Department of Ophthalmology, Kagoshima University Graduate School of Medical and 
      Dental Sciences, Kagoshima, Japan.
FAU - Sakamoto, Taiji
AU  - Sakamoto T
AD  - Department of Ophthalmology, Kagoshima University Graduate School of Medical and 
      Dental Sciences, Kagoshima, Japan.
FAU - Kakiuchi, Naoko
AU  - Kakiuchi N
AD  - Department of Ophthalmology, Kagoshima University Graduate School of Medical and 
      Dental Sciences, Kagoshima, Japan.
FAU - Tanaka, Minoru
AU  - Tanaka M
AD  - Department of Ophthalmology, Kagoshima University Graduate School of Medical and 
      Dental Sciences, Kagoshima, Japan.
FAU - Kii, Yuya
AU  - Kii Y
AD  - Department of Ophthalmology, Kagoshima University Graduate School of Medical and 
      Dental Sciences, Kagoshima, Japan.
FAU - Nakao, Kumiko
AU  - Nakao K
AD  - Department of Ophthalmology, Kagoshima University Graduate School of Medical and 
      Dental Sciences, Kagoshima, Japan.
LA  - eng
PT  - Journal Article
DEP - 20140812
PL  - United States
TA  - Invest Ophthalmol Vis Sci
JT  - Investigative ophthalmology & visual science
JID - 7703701
SB  - IM
MH  - Adult
MH  - Axial Length, Eye
MH  - Cross-Sectional Studies
MH  - Female
MH  - Humans
MH  - Male
MH  - *Nerve Fibers
MH  - Prospective Studies
MH  - Refraction, Ocular
MH  - Regression Analysis
MH  - Retina/*anatomy & histology
MH  - Retinal Ganglion Cells/*cytology
MH  - Tomography, Optical Coherence/methods
MH  - Young Adult
OTO - NOTNLM
OT  - glaucoma posterior segment
OT  - image analysis
OT  - optical coherence tomography
OT  - retinal nerve fiber
OT  - retinal thickness
EDAT- 2014/08/15 06:00
MHDA- 2014/11/06 06:00
CRDT- 2014/08/14 06:00
PHST- 2014/08/14 06:00 [entrez]
PHST- 2014/08/15 06:00 [pubmed]
PHST- 2014/11/06 06:00 [medline]
AID - iovs.13-13828 [pii]
AID - 10.1167/iovs.13-13828 [doi]
PST - epublish
SO  - Invest Ophthalmol Vis Sci. 2014 Aug 12;55(9):5673-8. doi: 10.1167/iovs.13-13828.