PMID- 25129008 OWN - NLM STAT- MEDLINE DCOM- 20150413 LR - 20161125 IS - 0974-7559 (Electronic) IS - 0019-6061 (Linking) VI - 51 IP - 8 DP - 2014 Aug TI - Immune reconstitution inflammatory syndrome in CNS tuberculosis. PG - 668-70 AB - BACKGROUND: Immune Reconstitution Inflammatory Syndrome (IRIS), an exaggerated inflammatory response with clinical worsening due to immune recovery during treatment, is rare in the immune-competent population. CASE CHARACTERISTICS: A 5-(1/2)-year old immune-competent girl with CNS tuberculosis without HIV who developed paradoxical IRIS. OUTCOME: Response to supportive care along with Anti-tuberculosis treatment. MESSAGE: IRIS can occur in tuberculosis, even in the immuno-competent. FAU - Elizabeth, K E AU - Elizabeth KE AD - Department of Pediatrics, SAT Hospital, Government Medical College, Thiruvananthapuram, Kerala, India. Correspondence to: Dr KE Elizabeth, Professor of Pediatrics and Superintendent, SAT Hospital, Government Medical College, Thiruvananthapuram, Kerala, India 695 011. elizake@hotmail.com. FAU - Jubin, K AU - Jubin K LA - eng PT - Case Reports PT - Journal Article PL - India TA - Indian Pediatr JT - Indian pediatrics JID - 2985062R RN - 0 (Anti-Inflammatory Agents) RN - 0 (Antitubercular Agents) RN - 9PHQ9Y1OLM (Prednisolone) SB - IM MH - Anti-Inflammatory Agents/therapeutic use MH - Antitubercular Agents/therapeutic use MH - Brain/diagnostic imaging/pathology MH - Child, Preschool MH - Female MH - Humans MH - *Immune Reconstitution Inflammatory Syndrome MH - Prednisolone/therapeutic use MH - Radiography MH - *Tuberculosis, Central Nervous System EDAT- 2014/08/19 06:00 MHDA- 2015/04/14 06:00 CRDT- 2014/08/18 06:00 PHST- 2014/08/18 06:00 [entrez] PHST- 2014/08/19 06:00 [pubmed] PHST- 2015/04/14 06:00 [medline] PST - ppublish SO - Indian Pediatr. 2014 Aug;51(8):668-70.