PMID- 25129092 OWN - NLM STAT- MEDLINE DCOM- 20140908 LR - 20140818 IS - 0385-0684 (Print) IS - 0385-0684 (Linking) VI - 41 IP - 6 DP - 2014 Jun TI - [A patient with advanced breast cancer who developed bacterial meningitis after chemotherapy]. PG - 769-71 AB - A 76-year-old woman was admitted to our hospital because of a right breast tumor and a skin ulcer. The patient was diagnosed as having advanced breast cancer T4bN2M1(lung), Stage IV. A regimen of 5-fluorouracil(500mg/m2)with epirubicin(100mg/m / 2)and cyclophosphamide(500mg/m2)(FEC100)was administered. However, the patient was hospitalized 12 days later because of febrile neutropenia. The patient experienced a stiff neck the next day, and bacterial meningitis was diagnosed on the basis of cerebrospinal fluid examination. Antibacterial agents were administered according to the clinical practice guidelines of bacterial meningitis. The patient recovered and was discharged from our hospital 24 days after admission. Bacterial meningitis after chemotherapy is rare, but this could be progress to a serious condition. Early diagnosis and treatment are paramount in such cases. FAU - Shibata, Kenichi AU - Shibata K AD - Dept. of Gastroenterological, General, Breast and Thyroid Surgery, Yamagata University Faculty of Medicine. FAU - Suzuki, Akihiko AU - Suzuki A FAU - Suzuki, Takefumi AU - Suzuki T FAU - Sato, Tamie AU - Sato T FAU - Yamagishi, Takehito AU - Yamagishi T FAU - Kimura, Seishi AU - Kimura S FAU - Kimura, Wataru AU - Kimura W LA - jpn PT - Case Reports PT - English Abstract PT - Journal Article PL - Japan TA - Gan To Kagaku Ryoho JT - Gan to kagaku ryoho. Cancer & chemotherapy JID - 7810034 RN - 0 (Anti-Bacterial Agents) RN - 3Z8479ZZ5X (Epirubicin) RN - 8N3DW7272P (Cyclophosphamide) RN - U3P01618RT (Fluorouracil) SB - IM MH - Aged MH - Anti-Bacterial Agents/therapeutic use MH - Antineoplastic Combined Chemotherapy Protocols/*adverse effects/therapeutic use MH - Breast Neoplasms/*drug therapy/pathology MH - Cyclophosphamide/administration & dosage/adverse effects MH - Epirubicin/administration & dosage/adverse effects MH - Female MH - Fluorouracil/administration & dosage/adverse effects MH - Humans MH - Meningitis, Bacterial/*drug therapy/etiology MH - Neoplasm Staging EDAT- 2014/08/19 06:00 MHDA- 2014/09/10 06:00 CRDT- 2014/08/18 06:00 PHST- 2014/08/18 06:00 [entrez] PHST- 2014/08/19 06:00 [pubmed] PHST- 2014/09/10 06:00 [medline] PST - ppublish SO - Gan To Kagaku Ryoho. 2014 Jun;41(6):769-71.