PMID- 25130990
OWN - NLM
STAT- MEDLINE
DCOM- 20160601
LR  - 20220317
IS  - 1439-0272 (Electronic)
IS  - 0303-4569 (Linking)
VI  - 47
IP  - 6
DP  - 2015 Aug
TI  - How accurate is sperm morphology as an indicator of sperm function?
PG  - 720-3
LID - 10.1111/and.12324 [doi]
AB  - Sperm morphology has been consistently correlated with fertilisation success or 
      failure. The clinical relevance of the percentage normal spermatozoa has been a 
      widely discussed topic amongst infertility specialists and scientists. This study 
      aimed to evaluate the role of sperm morphology as an indicator of additional 
      sperm functions among 114 andrology referrals. The sperm functions that were 
      investigated included chromatin packaging quality (CMA3 test (n = 109), 
      zona-induced acrosome reaction (ZIAR test; n = 36), hemizona assay (HZI; n = 36) 
      and progressive motility (n = 47). Chromatin packaging quality had a negative and 
      significant (P = 0.0001, r = -0.74) correlation with the percentage normal 
      spermatozoa, while progressive motility had a significant and positive 
      correlation (P = 0.0001, 0.59). Accurate sperm morphology scoring as described by 
      the WHO 2010 manual can therefore be used as an indicator of specific sperm 
      functions.
CI  - (c) 2014 Blackwell Verlag GmbH.
FAU - Franken, D R
AU  - Franken DR
AD  - Department of Obstetrics & Gynecology, University of Free State, Bloemfontein, 
      South Africa.
LA  - eng
PT  - Journal Article
DEP - 20140804
PL  - Germany
TA  - Andrologia
JT  - Andrologia
JID - 0423506
RN  - 0 (Chromatin)
SB  - IM
MH  - Acrosome Reaction/physiology
MH  - Chromatin/physiology/ultrastructure
MH  - Humans
MH  - Male
MH  - Sperm Motility/physiology
MH  - Spermatozoa/physiology/*ultrastructure
OTO - NOTNLM
OT  - Sperm function
OT  - sperm morphology
EDAT- 2014/08/19 06:00
MHDA- 2016/06/02 06:00
CRDT- 2014/08/19 06:00
PHST- 2014/06/14 00:00 [accepted]
PHST- 2014/08/19 06:00 [entrez]
PHST- 2014/08/19 06:00 [pubmed]
PHST- 2016/06/02 06:00 [medline]
AID - 10.1111/and.12324 [doi]
PST - ppublish
SO  - Andrologia. 2015 Aug;47(6):720-3. doi: 10.1111/and.12324. Epub 2014 Aug 4.