PMID- 25138427
OWN - NLM
STAT- MEDLINE
DCOM- 20151009
LR  - 20240130
IS  - 1532-6551 (Electronic)
IS  - 1071-3581 (Linking)
VI  - 21
IP  - 6
DP  - 2014 Dec
TI  - Molecular imaging to predict ventricular arrhythmia in heart failure.
PG  - 1096-109
LID - 10.1007/s12350-014-9975-4 [doi]
AB  - Ventricular tachycardia (VT) is a major cause of sudden cardiac death (SCD) in 
      patients with heart failure (HF). Left ventricular ejection fraction (LVEF) and 
      heart failure class according to the New York Heart association (NYHA) are in 
      most common use to identify patients that may benefit from implantable 
      cardioverter defibrillator (ICD) therapy. But during 3 years of follow up only 
      35% of patients receive appropriate ICD action. Therefore, there is a continued 
      need for refinement of selection criteria for ICD implantation. In this regard, 
      molecular imaging of the autonomic nervous system, which plays a central role in 
      HF progression and cardiac electro-mechanical regulation, can make a substantial 
      contribution. This article reviews the currently available literature concerning 
      the value of molecular neuronal cardiac imaging for prediction of ventricular 
      arrhythmias in HF patients.
FAU - Wollenweber, Tim
AU  - Wollenweber T
AD  - Department of Nuclear Medicine, Hannover Medical School, Carl-Neuberg-Str. 1, 
      30625, Hannover, Germany.
FAU - Bengel, Frank M
AU  - Bengel FM
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20140820
PL  - United States
TA  - J Nucl Cardiol
JT  - Journal of nuclear cardiology : official publication of the American Society of 
      Nuclear Cardiology
JID - 9423534
RN  - 0 (Radiopharmaceuticals)
SB  - IM
MH  - Heart Failure/complications/*diagnostic imaging/*metabolism
MH  - Heart Ventricles/diagnostic imaging/innervation
MH  - Humans
MH  - Molecular Imaging/*methods
MH  - Prognosis
MH  - Radiopharmaceuticals/*pharmacokinetics
MH  - Sympathetic Nervous System/diagnostic imaging/metabolism
MH  - Tachycardia, Ventricular/*diagnostic imaging/etiology/*metabolism
MH  - Tomography, Emission-Computed/methods
EDAT- 2014/08/21 06:00
MHDA- 2015/10/10 06:00
CRDT- 2014/08/21 06:00
PHST- 2014/07/14 00:00 [received]
PHST- 2014/08/04 00:00 [accepted]
PHST- 2014/08/21 06:00 [entrez]
PHST- 2014/08/21 06:00 [pubmed]
PHST- 2015/10/10 06:00 [medline]
AID - S1071-3581(23)07380-4 [pii]
AID - 10.1007/s12350-014-9975-4 [doi]
PST - ppublish
SO  - J Nucl Cardiol. 2014 Dec;21(6):1096-109. doi: 10.1007/s12350-014-9975-4. Epub 
      2014 Aug 20.