PMID- 25140258
OWN - NLM
STAT- MEDLINE
DCOM- 20150511
LR  - 20211021
IS  - 1687-5443 (Electronic)
IS  - 2090-5904 (Print)
IS  - 1687-5443 (Linking)
VI  - 2014
DP  - 2014
TI  - The interplay between reproductive social stimuli and adult olfactory bulb 
      neurogenesis.
PG  - 497657
LID - 10.1155/2014/497657 [doi]
LID - 497657
AB  - Adult neurogenesis is a striking form of structural plasticity that adapts the 
      brain to the changing world. Accordingly, new neuron production is involved in 
      cognitive functions, such as memory, learning, and pattern separation. Recent 
      data in rodents indicate a close link between adult neurogenesis and reproductive 
      social behavior. This provides a key to unravel the functional meaning of adult 
      neurogenesis in biological relevant contexts and, in parallel, opens new 
      perspectives to explore the way the brain is processing social stimuli. In this 
      paper we will summarize some of the major achievements on cues and mechanisms 
      modulating adult neurogenesis during social behaviors related to reproduction and 
      possible role/s played by olfactory newborn neurons in this context. We will 
      point out that newborn interneurons in the accessory olfactory bulb (AOB) 
      represent a privileged cellular target for social stimuli that elicit 
      reproductive behaviors and that such cues modulate adult neurogenesis at two 
      different levels increasing both proliferation of neuronal progenitors in the 
      germinative regions and integration of newborn neurons into functional circuits. 
      This dual mechanism provides fresh neurons that can be involved in critical 
      activities for the individual fitness, that is, the processing of social stimuli 
      driving the parental behavior and partner recognition.
FAU - Peretto, Paolo
AU  - Peretto P
AUID- ORCID: 0000-0001-5502-6476
AD  - Department of Life Sciences and Systems Biology, University of Turin, Via 
      Accademia Albertina 13 ,10123 Torino, Italy ; Neuroscience Institute Cavalieri 
      Ottolenghi (NICO), Regione Gonzole 10, Orbassano, 10043 Torino, Italy.
FAU - Schellino, Roberta
AU  - Schellino R
AUID- ORCID: 0000-0002-2504-5585
AD  - Department of Life Sciences and Systems Biology, University of Turin, Via 
      Accademia Albertina 13 ,10123 Torino, Italy ; Neuroscience Institute Cavalieri 
      Ottolenghi (NICO), Regione Gonzole 10, Orbassano, 10043 Torino, Italy.
FAU - De Marchis, Silvia
AU  - De Marchis S
AD  - Department of Life Sciences and Systems Biology, University of Turin, Via 
      Accademia Albertina 13 ,10123 Torino, Italy ; Neuroscience Institute Cavalieri 
      Ottolenghi (NICO), Regione Gonzole 10, Orbassano, 10043 Torino, Italy.
FAU - Fasolo, Aldo
AU  - Fasolo A
AD  - Department of Life Sciences and Systems Biology, University of Turin, Via 
      Accademia Albertina 13 ,10123 Torino, Italy ; Neuroscience Institute Cavalieri 
      Ottolenghi (NICO), Regione Gonzole 10, Orbassano, 10043 Torino, Italy.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
DEP - 20140722
PL  - United States
TA  - Neural Plast
JT  - Neural plasticity
JID - 100883417
RN  - 0 (Pheromones)
SB  - IM
MH  - Age Factors
MH  - Animals
MH  - Brain/physiology
MH  - Cues
MH  - Female
MH  - Male
MH  - Mice
MH  - *Neurogenesis
MH  - Olfactory Bulb/*physiology
MH  - Pheromones/physiology
MH  - Rats
MH  - Sexual Behavior/*physiology
MH  - *Social Behavior
PMC - PMC4130132
EDAT- 2014/08/21 06:00
MHDA- 2015/05/12 06:00
PMCR- 2014/07/22
CRDT- 2014/08/21 06:00
PHST- 2014/04/22 00:00 [received]
PHST- 2014/06/19 00:00 [accepted]
PHST- 2014/08/21 06:00 [entrez]
PHST- 2014/08/21 06:00 [pubmed]
PHST- 2015/05/12 06:00 [medline]
PHST- 2014/07/22 00:00 [pmc-release]
AID - 10.1155/2014/497657 [doi]
PST - ppublish
SO  - Neural Plast. 2014;2014:497657. doi: 10.1155/2014/497657. Epub 2014 Jul 22.