PMID- 25145982
OWN - NLM
STAT- MEDLINE
DCOM- 20150702
LR  - 20220330
IS  - 1439-6327 (Electronic)
IS  - 1439-6319 (Linking)
VI  - 114
IP  - 12
DP  - 2014 Dec
TI  - Acute leukocyte, cytokine and adipocytokine responses to maximal and hypertrophic 
      resistance exercise bouts.
PG  - 2607-16
LID - 10.1007/s00421-014-2979-6 [doi]
AB  - The purpose of this study was to examine the acute immune response (circulating 
      levels of leukocytes, cytokines and adipocytokines) to maximal resistance (MAX, 
      15 x 1RM) and hypertrophic resistance (HYP, 5 x 10RM) exercise bouts. Twelve 
      healthy men (age = 28.2 +/- 3.5 years, weight = 78.6 +/- 10.4 kg, height 178.8 +/- 5.0 
      cm, fat percentage = 16.5 +/- 3.5 %) participated in the study. Blood was sampled 
      before, immediately after and 15 and 30 min after exercise. Leukocytes (WBC) 
      significantly increased immediately after HYP (p < 0.01), whereas in MAX, 
      increases in WBC became significant after 30 min (p < 0.05). Lymphocytes 
      increased only after HYP (p < 0.001), while MAX induced lymphopenia during 
      recovery (p < 0.01). Monocyte chemoattractant protein-1 (MCP-1) decreased (p < 
      0.05) and interleukin-1 receptor antagonist (IL-1ra) increased after HYP, which 
      were not observed after MAX. Adipsin and resistin decreased after both exercise 
      bouts (p < 0.05), which suggest that heavy resistance exercise is at least 
      transiently beneficial for adipocytokine profile. Immediate mechanical stress 
      seemed similar as no differences in myoglobin response were observed. The higher 
      magnitude of metabolic demand reflected in higher lactate response in HYP could 
      be the reason for the significantly high responses in WBC, IL-1ra and decrease in 
      MCP-1.
FAU - Ihalainen, Johanna
AU  - Ihalainen J
AD  - Department of Biology of Physical Activity, University of Jyvaskyla, P.O Box 35, 
      40014, Jyvaskyla, Finland, johanna.stenholm@jyu.fi.
FAU - Walker, Simon
AU  - Walker S
FAU - Paulsen, Goran
AU  - Paulsen G
FAU - Hakkinen, Keijo
AU  - Hakkinen K
FAU - Kraemer, William J
AU  - Kraemer WJ
FAU - Hamalainen, Mari
AU  - Hamalainen M
FAU - Vuolteenaho, Katriina
AU  - Vuolteenaho K
FAU - Moilanen, Eeva
AU  - Moilanen E
FAU - Mero, Antti A
AU  - Mero AA
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20140822
PL  - Germany
TA  - Eur J Appl Physiol
JT  - European journal of applied physiology
JID - 100954790
RN  - 0 (Adipokines)
RN  - 0 (Cytokines)
SB  - IM
MH  - Adipokines/*blood
MH  - Adult
MH  - Body Composition/physiology
MH  - Cytokines/*blood
MH  - Exercise/*physiology
MH  - Humans
MH  - Leukocyte Count
MH  - Leukocytes/*cytology
MH  - Male
MH  - *Resistance Training
EDAT- 2014/08/26 06:00
MHDA- 2015/07/03 06:00
CRDT- 2014/08/23 06:00
PHST- 2014/03/24 00:00 [received]
PHST- 2014/08/05 00:00 [accepted]
PHST- 2014/08/23 06:00 [entrez]
PHST- 2014/08/26 06:00 [pubmed]
PHST- 2015/07/03 06:00 [medline]
AID - 10.1007/s00421-014-2979-6 [doi]
PST - ppublish
SO  - Eur J Appl Physiol. 2014 Dec;114(12):2607-16. doi: 10.1007/s00421-014-2979-6. 
      Epub 2014 Aug 22.