PMID- 25156691
OWN - NLM
STAT- MEDLINE
DCOM- 20150706
LR  - 20211021
IS  - 1875-8312 (Electronic)
IS  - 1569-5794 (Linking)
VI  - 30 Suppl 2
DP  - 2014 Dec
TI  - Cardiovascular magnetic resonance tagging imaging correlates with myocardial 
      dysfunction and T2 mapping in idiopathic dilated cardiomyopathy.
PG  - 145-52
LID - 10.1007/s10554-014-0523-8 [doi]
AB  - To evaluate the details of myocardial dysfunction in dilated cardiomyopathy (DCM) 
      patients using tagging images and the correlation of tagging imaging with tissue 
      characteristics. Circumferential strain (Ecc) derived from tagging images was 
      measured in 15 normal (NML) subjects (15 males; mean age 28.5 years) and 12 DCM 
      patients (7 males; mean age 48.9 years). The following parameters were compared: 
      (1) the magnitude of peak Ecc (Ecc*); (2) the coefficient of variation of the 
      time of Ecc* (CVtime*), which indexes dyssynchrony; and (3) descriptive findings 
      of time-Ecc curves. We also evaluated the correlations of Ecc* in DCM patients 
      with ejection fraction (EF), myocardial T2 values, and late gadolinium 
      enhancement (LGE). Mean Ecc*s in DCM patients and NML subjects were -12.7 and 
      -23.5%, respectively (P < 0.0001). Mean CVtime*s were 15.2 and 4.5%, respectively 
      (P = 0.0002). The findings of pre-systolic extension and systolic stretch in the 
      septum were observed in 6 (50%) and 10 (83.3%) DCM patients and in none of the 
      NML participants. Ecc* was correlated with EF (P < 0.0001, R2 = 0.90) and T2 
      values (P = 0.018, R2 = 0.44) but not with LGE (P = 0.072, R2 = 0.28). Tagging 
      images revealed the reduction of myocardial function as well as dyssynchrony in 
      DCM patients. Myocardial dysfunction occurred coincidently with myocardial 
      inflammation.
FAU - Kono, Atsushi K
AU  - Kono AK
AD  - Department of Radiology, Kobe University Hospital, 7-5-2 Kusunoki-cho, Chuo-ku, 
      Kobe, Hyogo, 650-0017, Japan, ringonotegami@mac.com.
FAU - Croisille, Pierre
AU  - Croisille P
FAU - Nishii, Tatsuya
AU  - Nishii T
FAU - Nishiyama, Koya
AU  - Nishiyama K
FAU - Kyotani, Katsusuke
AU  - Kyotani K
FAU - Shigeru, Mayumi
AU  - Shigeru M
FAU - Takamine, Sachiko
AU  - Takamine S
FAU - Fujiwara, Sei
AU  - Fujiwara S
FAU - Sugimura, Kazuro
AU  - Sugimura K
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20140826
PL  - United States
TA  - Int J Cardiovasc Imaging
JT  - The international journal of cardiovascular imaging
JID - 100969716
RN  - 0 (Contrast Media)
RN  - K2I13DR72L (Gadolinium DTPA)
SB  - IM
MH  - Adult
MH  - Cardiomyopathy, Dilated/*diagnosis/pathology/physiopathology
MH  - Contrast Media
MH  - Female
MH  - Gadolinium DTPA
MH  - Humans
MH  - Image Interpretation, Computer-Assisted/*methods
MH  - Magnetic Resonance Imaging, Cine/*methods
MH  - Male
MH  - Middle Aged
MH  - *Myocardial Contraction
MH  - Myocardium/pathology
MH  - Predictive Value of Tests
MH  - Retrospective Studies
MH  - Ventricular Dysfunction/*diagnosis/pathology/physiopathology
MH  - *Ventricular Function
EDAT- 2014/08/27 06:00
MHDA- 2015/07/07 06:00
CRDT- 2014/08/27 06:00
PHST- 2014/07/16 00:00 [received]
PHST- 2014/08/15 00:00 [accepted]
PHST- 2014/08/27 06:00 [entrez]
PHST- 2014/08/27 06:00 [pubmed]
PHST- 2015/07/07 06:00 [medline]
AID - 10.1007/s10554-014-0523-8 [doi]
PST - ppublish
SO  - Int J Cardiovasc Imaging. 2014 Dec;30 Suppl 2:145-52. doi: 
      10.1007/s10554-014-0523-8. Epub 2014 Aug 26.