PMID- 25168723
OWN - NLM
STAT- MEDLINE
DCOM- 20150527
LR  - 20211021
IS  - 1475-925X (Electronic)
IS  - 1475-925X (Linking)
VI  - 13
DP  - 2014 Aug 28
TI  - Thermal, creep-recovery and viscoelastic behavior of high density 
      polyethylene/hydroxyapatite nano particles for bone substitutes: effects of gamma 
      radiation.
PG  - 125
LID - 10.1186/1475-925X-13-125 [doi]
LID - 125
AB  - BACKGROUND: High Density Polyethylene (HDPE) is one of the most often used 
      polymers in biomedical applications. The limitations of HDPE are its 
      visco-elastic behavior, low modulus and poor bioactivity. To improve HDPE 
      properties, HA nanoparticles can be added to form polymer composite that can be 
      used as alternatives to metals for bone substitutes and orthopaedic implant 
      applications. METHOD: In our previous work (BioMedical Engineering OnLine 2013), 
      different ratios of HDPE/HA nanocomposites were prepared using melt blending in a 
      co-rotating intermeshing twin screw extruder. The accelerated aging effects on 
      the tensile properties and torsional viscoelastic behavior (storage modulus (G') 
      and Loss modulus (G")) at 80 degrees C of irradiated and non-irradiated HDPE/HA was 
      investigated. Also the thermal behavior of HDPE/HA were studied. In this study, 
      the effects of gamma irradiation on the tensile viscoelastic behavior (storage 
      modulus (E') and Loss modulus (E")) at 25 degrees C examined for HDPE/HA nanocomposites 
      at different frequencies using Dynamic Mechanical Analysis (DMA). The DMA was 
      also used to analyze creep-recovery and relaxation properties of the 
      nanocomposites. To analyze the thermal behavior of the HDPE/HA nanocomposite, 
      Differential Scanning Calorimetry (DSC) was used. RESULTS: The microscopic 
      examination of the cryogenically fractured surface revealed a reasonable 
      distribution of HA nanoparticles in the HDPE matrix. The DMA showed that the 
      tensile storage and loss modulus increases with increasing the HA nanoparticles 
      ratio and the test frequency. The creep-recovery behavior improves with 
      increasing the HA nanoparticle content. Finally, the results indicated that the 
      crystallinity, viscoelastic, creep recovery and relaxation behavior of HDPE 
      nanocomposite improved due to gamma irradiation. CONCLUSION: Based on the 
      experimental results, it is found that prepared HDPE nanocomposite properties 
      improved due to the addition of HA nanoparticles and irradiation. So, the 
      prepared HDPE/HA nanocomposite appears to have fairly good comprehensive 
      properties that make it a good candidate as bone substitute.
FAU - Alothman, Othman Y
AU  - Alothman OY
FAU - Fouad, H
AU  - Fouad H
AD  - Applied Medical Science Department, Riyadh Community College, King Saud 
      University, Riyadh, Saudi Arabia. menhfefnew@hotmail.com.
FAU - Al-Zahrani, S M
AU  - Al-Zahrani SM
FAU - Eshra, Ayman
AU  - Eshra A
FAU - Al Rez, Mohammed Fayez
AU  - Al Rez MF
FAU - Ansari, S G
AU  - Ansari SG
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20140828
PL  - England
TA  - Biomed Eng Online
JT  - Biomedical engineering online
JID - 101147518
RN  - 0 (Biocompatible Materials)
RN  - 0 (Bone Substitutes)
RN  - 9002-88-4 (Polyethylene)
RN  - 91D9GV0Z28 (Durapatite)
SB  - IM
MH  - Biocompatible Materials/chemistry/radiation effects
MH  - Bone Substitutes/*chemistry/radiation effects
MH  - Calorimetry
MH  - Durapatite/*chemistry/radiation effects
MH  - Gamma Rays
MH  - Nanocomposites/*chemistry/radiation effects
MH  - Nanoparticles/*chemistry/radiation effects
MH  - Polyethylene/*chemistry/radiation effects
MH  - Viscosity
PMC - PMC4156649
EDAT- 2014/08/30 06:00
MHDA- 2015/05/28 06:00
PMCR- 2014/08/28
CRDT- 2014/08/30 06:00
PHST- 2014/05/14 00:00 [received]
PHST- 2014/08/21 00:00 [accepted]
PHST- 2014/08/30 06:00 [entrez]
PHST- 2014/08/30 06:00 [pubmed]
PHST- 2015/05/28 06:00 [medline]
PHST- 2014/08/28 00:00 [pmc-release]
AID - 1475-925X-13-125 [pii]
AID - 861 [pii]
AID - 10.1186/1475-925X-13-125 [doi]
PST - epublish
SO  - Biomed Eng Online. 2014 Aug 28;13:125. doi: 10.1186/1475-925X-13-125.