PMID- 25171459 OWN - NLM STAT- MEDLINE DCOM- 20150602 LR - 20211021 IS - 1423-0151 (Electronic) IS - 1011-7571 (Print) IS - 1011-7571 (Linking) VI - 23 IP - 5 DP - 2014 TI - Comparison of three tracheal intubation techniques in thyroid tumor patients with a difficult airway: a randomized controlled trial. PG - 448-52 LID - 10.1159/000364875 [doi] AB - OBJECTIVE: To investigate the effectiveness of the Shikani optical stylet (SOS) and GlideScope video laryngoscope (GVL) for tracheal intubation of thyroid tumor patients with a difficult airway. SUBJECTS AND METHODS: One hundred and twenty thyroid tumor patients with a difficult airway, who were undergoing elective surgery requiring general anesthesia, were enrolled in the study. They were randomly allocated to 3 groups (n = 40 each) who underwent direct laryngoscopy (DL), SOS or GVL. The outcomes recorded were time to intubation, first-attempt success rate, mean artery pressure (MAP), heart rate (HR) and incidence of complications. RESULTS: The mean time to intubation in the SOS group (group S; 42.4 +/- 24.1 s) and the GLV group (group G; 29.8 +/- 22.3 s) was significantly less than that in the DL group (group D) (68.8 +/- 26.6 s). The first-attempt success rate in group S (90.0%) and group G (97.5%) was significantly higher than that in group D (75.0%; all p < 0.05). The HR and MAP at 1 min after intubation were lowest in group S (76.4 +/- 9.2 beats/min and 12.9 +/- 1.1 kPa), followed by group G (79.9 +/- 9.3 beats/min and 13.0 +/- 0.9 kPa) and then group D (90.4 +/- 8.1 beats/min and 16.6 +/- 1.2 kPa). The difference was statistically significant (all p < 0.05). The incidence of lip or mucosal trauma was lowest in group S, followed by group G and then group D. CONCLUSION: The SOS and the GLV had advantages over the DL in the management of thyroid tumor patients with a difficult airway in terms of a shorter time to intubation, a higher first-attempt success rate and a reduced incidence of complications. Thus, a rational choice of one of these techniques may be better for the perioperative safety of thyroid tumor patients with a difficult airway. CI - (c) 2014 S. Karger AG, Basel. FAU - Liu, Ling AU - Liu L AD - Department of Anesthesiology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, China. FAU - Yue, Hui AU - Yue H FAU - Li, Jincheng AU - Li J LA - eng PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial DEP - 20140823 PL - Switzerland TA - Med Princ Pract JT - Medical principles and practice : international journal of the Kuwait University, Health Science Centre JID - 8901334 SB - IM MH - Adult MH - Anesthesia, General MH - Blood Pressure MH - Elective Surgical Procedures MH - Female MH - Heart Rate MH - Humans MH - Intubation, Intratracheal/adverse effects/*instrumentation/methods MH - *Laryngoscopes MH - *Laryngoscopy MH - Male MH - Middle Aged MH - Operative Time MH - Thyroid Neoplasms/*pathology/*surgery PMC - PMC5586920 EDAT- 2014/08/30 06:00 MHDA- 2015/06/03 06:00 PMCR- 2014/08/23 CRDT- 2014/08/30 06:00 PHST- 2013/11/28 00:00 [received] PHST- 2014/05/27 00:00 [accepted] PHST- 2014/08/30 06:00 [entrez] PHST- 2014/08/30 06:00 [pubmed] PHST- 2015/06/03 06:00 [medline] PHST- 2014/08/23 00:00 [pmc-release] AID - 000364875 [pii] AID - mpp-0023-0448 [pii] AID - 10.1159/000364875 [doi] PST - ppublish SO - Med Princ Pract. 2014;23(5):448-52. doi: 10.1159/000364875. Epub 2014 Aug 23.