PMID- 25172727
OWN - NLM
STAT- MEDLINE
DCOM- 20151214
LR  - 20181202
IS  - 1873-7072 (Electronic)
IS  - 0308-8146 (Linking)
VI  - 168
DP  - 2015 Feb 1
TI  - Analysis of benzobicyclon and its metabolite in brown rice and rice straw after 
      field application using liquid chromatography-tandem mass spectrometry.
PG  - 404-9
LID - S0308-8146(14)01144-3 [pii]
LID - 10.1016/j.foodchem.2014.07.096 [doi]
AB  - This study was carried out to develop an extraction as well as an analytical 
      method for detecting benzobicyclon and its amino-substituted metabolite 
      (1315P-570) in brown rice and rice straw using liquid chromatography-tandem mass 
      spectrometry (LC/MS/MS) in positive ion mode with multiple reaction monitoring 
      (MRM). The parent as well as the metabolite in rice and rice straw were extracted 
      and analysed under the same conditions. A correlation coefficient (R(2)) of 
      >0.994 was obtained for matrix-matched calibration curves constructed in various 
      concentration ranges. Recoveries at two fortification levels were satisfactory 
      and ranged between 75.4% and 118.9% with relative standard deviations (RSDs)<13%. 
      Under storage conditions (-20 degrees C), the analyte and its metabolite were stable for 
      up to 92days. The limits of quantitation (LOQ) were lower than the maximum 
      residue limit (MRL) (0.1mg/kg) set by the Korea Food and Drug Administration for 
      brown rice. Field trials with recommended or double the recommended dose revealed 
      that the herbicide could safely be applied to rice and rice straw, as no residues 
      were detected in the harvested samples. The sensitivity of the developed method 
      was sufficient to ensure reliable determination of benzobicyclon and its 
      metabolite in rice grain and rice straw.
CI  - Copyright (c) 2014 Elsevier Ltd. All rights reserved.
FAU - Im, So Jeong
AU  - Im SJ
AD  - Biotechnology Research Institute, Chonnam National University, 77 Yongbong-ro, 
      Buk-gu, Gwangju 500-757, Republic of Korea.
FAU - Abd El-Aty, A M
AU  - Abd El-Aty AM
AD  - Biotechnology Research Institute, Chonnam National University, 77 Yongbong-ro, 
      Buk-gu, Gwangju 500-757, Republic of Korea; Department of Pharmacology, Faculty 
      of Veterinary Medicine, Cairo University, 12211 Giza, Egypt. Electronic address: 
      abdelaty44@hotmail.com.
FAU - Lee, Young-Jun
AU  - Lee YJ
AD  - Biotechnology Research Institute, Chonnam National University, 77 Yongbong-ro, 
      Buk-gu, Gwangju 500-757, Republic of Korea.
FAU - Rahman, Md Musfiqur
AU  - Rahman MM
AD  - Biotechnology Research Institute, Chonnam National University, 77 Yongbong-ro, 
      Buk-gu, Gwangju 500-757, Republic of Korea.
FAU - Kim, Sung-Woo
AU  - Kim SW
AD  - Biotechnology Research Institute, Chonnam National University, 77 Yongbong-ro, 
      Buk-gu, Gwangju 500-757, Republic of Korea.
FAU - Choi, Jeong-Heui
AU  - Choi JH
AD  - Biotechnology Research Institute, Chonnam National University, 77 Yongbong-ro, 
      Buk-gu, Gwangju 500-757, Republic of Korea.
FAU - Shim, Jae-Han
AU  - Shim JH
AD  - Biotechnology Research Institute, Chonnam National University, 77 Yongbong-ro, 
      Buk-gu, Gwangju 500-757, Republic of Korea. Electronic address: 
      jhshim@chonnam.ac.kr.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20140724
PL  - England
TA  - Food Chem
JT  - Food chemistry
JID - 7702639
RN  - 0 (Bridged Bicyclo Compounds)
RN  - 0 (Herbicides)
RN  - 0 (Pesticide Residues)
RN  - 0 (Sulfones)
RN  - 0 (benzobicyclon)
SB  - IM
MH  - Bridged Bicyclo Compounds/*analysis/metabolism
MH  - Chromatography, Liquid/*methods
MH  - Herbicides/*analysis/metabolism
MH  - Limit of Detection
MH  - Oryza/*chemistry
MH  - Pesticide Residues/*analysis
MH  - Sulfones/*analysis/metabolism
MH  - Tandem Mass Spectrometry/*methods
OTO - NOTNLM
OT  - Analysis
OT  - Herbicide
OT  - Metabolite
OT  - Residue
OT  - Rice straw
OT  - Unpolished rice
EDAT- 2014/08/31 06:00
MHDA- 2015/12/15 06:00
CRDT- 2014/08/31 06:00
PHST- 2014/03/07 00:00 [received]
PHST- 2014/06/10 00:00 [revised]
PHST- 2014/07/17 00:00 [accepted]
PHST- 2014/08/31 06:00 [entrez]
PHST- 2014/08/31 06:00 [pubmed]
PHST- 2015/12/15 06:00 [medline]
AID - S0308-8146(14)01144-3 [pii]
AID - 10.1016/j.foodchem.2014.07.096 [doi]
PST - ppublish
SO  - Food Chem. 2015 Feb 1;168:404-9. doi: 10.1016/j.foodchem.2014.07.096. Epub 2014 
      Jul 24.