PMID- 25183177
OWN - NLM
STAT- MEDLINE
DCOM- 20150129
LR  - 20220910
IS  - 1808-8686 (Electronic)
IS  - 1808-8694 (Print)
IS  - 1808-8686 (Linking)
VI  - 80
IP  - 4
DP  - 2014 Jul-Aug
TI  - Sinonasal disorders in hematopoietic stem cell transplantation.
PG  - 285-9
LID - S1808-8694(14)00027-5 [pii]
LID - 10.1016/j.bjorl.2014.05.009 [doi]
AB  - INTRODUCTION: hematopoietic stem cell transplantation (HSCT) is associated with 
      more respiratory infections due to immunosuppression. OBJECTIVE: this study aimed 
      to verify the frequency of rhinosinusitis after HSCT, and the association between 
      rhinosinusitis and chronic graft vs. host disease (GVHD) and type of 
      transplantation, clinical treatment, surgical treatment, and survival. METHODS: 
      this was a retrospective study in a tertiary university hospital. A total of 95 
      patients with hematological diseases undergoing HSCT between 1996 and 2011 were 
      selected. RESULTS: chronic myeloid leukemia was the most prevalent disease. The 
      type of transplant most often performed was the allogenic type (85.26%). The 
      frequency of rhinosinusitis was 36%, with no difference between the autologous 
      and the allogenic types. Chronic GVHD occurred in 30% of patients. Patients with 
      GVHD had a higher frequency and recurrence of rhinosinusitis, in addition to more 
      frequent need for endoscopic sinusectomy and decreased overall survival. 
      CONCLUSION: there was a higher frequency of rhinosinusitis in HSCT and GVHD. The 
      type of transplant does not appear to predispose to the occurrence of 
      rhinosinusitis. GVHD seems to be an aggravating factor and requires a more 
      stringent treatment.
CI  - Copyright (c) 2014 Associacao Brasileira de Otorrinolaringologia e Cirurgia 
      Cervico-Facial. Published by Elsevier Editora Ltda. All rights reserved.
FAU - Bento, Lucas Ricci
AU  - Bento LR
AD  - Discipline of Otorhinolaryngology, Faculdade de Ciencias Medicas, Universidade 
      Estadual de Campinas (UNICAMP), Campinas, SP, Brazil.
FAU - Ortiz, Erica
AU  - Ortiz E
AD  - Discipline of Otorhinolaryngology, Faculdade de Ciencias Medicas, Universidade 
      Estadual de Campinas (UNICAMP), Campinas, SP, Brazil. Electronic address: 
      erica.ortiz@terra.com.br.
FAU - Nicola, Ester Maria Danieli
AU  - Nicola EM
AD  - Discipline of Otorhinolaryngology, Faculdade de Ciencias Medicas, Universidade 
      Estadual de Campinas (UNICAMP), Campinas, SP, Brazil.
FAU - Vigorito, Afonso C
AU  - Vigorito AC
AD  - Hemocentro, Universidade Estadual de Campinas (UNICAMP), Campinas, SP, Brazil.
FAU - Sakano, Eulalia
AU  - Sakano E
AD  - Discipline of Otorhinolaryngology, Faculdade de Ciencias Medicas, Universidade 
      Estadual de Campinas (UNICAMP), Campinas, SP, Brazil.
LA  - eng
PT  - Journal Article
DEP - 20140611
PL  - Brazil
TA  - Braz J Otorhinolaryngol
JT  - Brazilian journal of otorhinolaryngology
JID - 101207337
SB  - IM
MH  - Chronic Disease
MH  - *Graft vs Host Disease
MH  - Hematologic Diseases/*surgery
MH  - Hematopoietic Stem Cell Transplantation/*adverse effects
MH  - Humans
MH  - Retrospective Studies
MH  - Rhinitis/diagnosis/*etiology
MH  - Sinusitis/diagnosis/*etiology
PMC - PMC9444614
OTO - NOTNLM
OT  - Condutas terapeuticas
OT  - Doenca enxerto-hospedeiro
OT  - Graft vs. host disease
OT  - Hematopoietic stem cell transplantation
OT  - Sinusite
OT  - Sinusitis
OT  - Therapeutic conducts
OT  - Transplante de celulas-tronco hematopoeticas
EDAT- 2014/09/04 06:00
MHDA- 2015/01/30 06:00
PMCR- 2014/06/11
CRDT- 2014/09/04 06:00
PHST- 2013/01/17 00:00 [received]
PHST- 2014/02/16 00:00 [accepted]
PHST- 2014/09/04 06:00 [entrez]
PHST- 2014/09/04 06:00 [pubmed]
PHST- 2015/01/30 06:00 [medline]
PHST- 2014/06/11 00:00 [pmc-release]
AID - S1808-8694(14)00027-5 [pii]
AID - 10.1016/j.bjorl.2014.05.009 [doi]
PST - ppublish
SO  - Braz J Otorhinolaryngol. 2014 Jul-Aug;80(4):285-9. doi: 
      10.1016/j.bjorl.2014.05.009. Epub 2014 Jun 11.