PMID- 25183368
OWN - NLM
STAT- MEDLINE
DCOM- 20151110
LR  - 20211021
IS  - 1435-165X (Electronic)
IS  - 1018-8827 (Linking)
VI  - 24
IP  - 5
DP  - 2015 May
TI  - Long-term effectiveness of electroconvulsive therapy in adolescents with 
      schizophrenia spectrum disorders.
PG  - 517-24
LID - 10.1007/s00787-014-0602-3 [doi]
AB  - To compare a sample of adolescents with schizophrenia spectrum disorders (SSD) 
      treated with either ECT or antipsychotics (AP) alone at long-term follow-up. 
      Patients diagnosed with SSD (n = 21) treated with ECT due to resistance to AP or 
      catatonia under the age of 18 years (ECT group), were compared to a randomly 
      selected group of patients with SSD treated only with AP (non-ECT group) (n = 21) 
      and matched for age, gender, diagnosis and duration of illness. Baseline data 
      were gathered retrospectively from medical records. Subjects were assessed at 
      follow-up (mean of follow-up period = 5.5 years; range 2-9 years) using several 
      clinical scales such as the Positive and Negative Syndrome Scale (PANSS), the 
      Clinical Global Impression Scale (CGI) and the Global Assessment of Functioning 
      (GAF). Improvement in PANSS positive, negative, general, total and CGI and GAF 
      scores between baseline and follow-up assessment did not differ significantly 
      between groups. At follow-up, no differences were observed for the PANSS 
      negative, CGI and GAF scores between groups, but patients in the ECT group still 
      had higher PANSS total, positive and general scores. ECT treatment followed by AP 
      medication in treatment-resistant SSD or catatonia is at least as effective in 
      the long term as AP alone in non-resistant patients.
FAU - Flamarique, Itziar
AU  - Flamarique I
AD  - Department of Child and Adolescent Psychiatry and Psychology, SGR1119, Institut 
      Clinic de Neurociencies, Hospital Clinic Universitari de Barcelona, C/Villarroel, 
      170, 08036, Barcelona, Spain, itziar.flamarike@gmail.com.
FAU - Baeza, Inmaculada
AU  - Baeza I
FAU - de la Serna, Elena
AU  - de la Serna E
FAU - Pons, Alexandre
AU  - Pons A
FAU - Bernardo, Miguel
AU  - Bernardo M
FAU - Castro-Fornieles, Josefina
AU  - Castro-Fornieles J
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20140903
PL  - Germany
TA  - Eur Child Adolesc Psychiatry
JT  - European child & adolescent psychiatry
JID - 9212296
RN  - 0 (Antipsychotic Agents)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Antipsychotic Agents/*therapeutic use
MH  - Catatonia/therapy
MH  - Combined Modality Therapy
MH  - *Electroconvulsive Therapy
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Male
MH  - Medical Records
MH  - Retrospective Studies
MH  - Schizophrenia/drug therapy/*therapy
MH  - Schizophrenia, Catatonic/therapy
MH  - *Schizophrenic Psychology
MH  - Time Factors
MH  - Treatment Outcome
EDAT- 2014/09/04 06:00
MHDA- 2015/11/11 06:00
CRDT- 2014/09/04 06:00
PHST- 2014/04/13 00:00 [received]
PHST- 2014/08/12 00:00 [accepted]
PHST- 2014/09/04 06:00 [entrez]
PHST- 2014/09/04 06:00 [pubmed]
PHST- 2015/11/11 06:00 [medline]
AID - 10.1007/s00787-014-0602-3 [doi]
PST - ppublish
SO  - Eur Child Adolesc Psychiatry. 2015 May;24(5):517-24. doi: 
      10.1007/s00787-014-0602-3. Epub 2014 Sep 3.