PMID- 2518662
OWN - NLM
STAT- MEDLINE
DCOM- 19910326
LR  - 20061115
IS  - 0025-7680 (Print)
IS  - 0025-7680 (Linking)
VI  - 49
IP  - 4
DP  - 1989
TI  - Dynamics of transmission of Trypanosoma cruzi in a rural area of Argentina. IV. 
      Serologic, parasitologic and electrocardiographic study of the human population.
PG  - 341-50
AB  - A serologic and electrocardiographic study was carried out in people living in 18 
      households in La Invernada (LI), Departamento Figueroa, and in 20 houses in Amama 
      (A), Departamento Moreno, both in the province of Santiago del Estero, Argentina. 
      Serological tests performed were indirect hemagglutination (IHAT) and indirect 
      immunofluorescence antibody tests (IFAT). Complement fixation, direct 
      agglutination and ELISA tests were also done for those sera, showing discordant 
      results for either IHAT or IFAT. All people in LI and children up to 12 years old 
      in A were studied by xenodiagnosis. Approximately 50% of the whole population was 
      infected (50% in LI and 50.9% in A) and a similar prevalence rate was already 
      recorded in children below 10 years. A moderate increase of infection rates was 
      observed in successively older age groups, indicating that most of the people 
      became infected in the first decade of life. Comparison of serological profiles 
      of both populations suggests a protective effect of insecticidal control 
      campaigns in those individuals born between 1961 and 1971. New surveys carried 
      out in both populations 2 years later rendered a 4 times greater annual incidence 
      rate in A as compared with LI (7.9% vs 1.8% respectively). No differences were 
      found in the percentages of abnormal electrocardiograms among seropositive and 
      seronegative individuals from both settlements. The prevalence of complete right 
      bundle branch block (RBBB) was higher in seropositive than in seronegative people 
      (4.8% vs 2.3%) but lower than those figures recorded for other parts of the 
      country and the continent. This suggests that in spite of its high prevalence, 
      Chagas' disease has low morbidity in both localities.
FAU - Wisnivesky-Colli, C
AU  - Wisnivesky-Colli C
FAU - Ruiz, A M
AU  - Ruiz AM
FAU - Gurtler, R E
AU  - Gurtler RE
FAU - Solarz, N D
AU  - Solarz ND
FAU - Lazzari, J
AU  - Lazzari J
FAU - Ledesma, O
AU  - Ledesma O
FAU - Bujas, M A
AU  - Bujas MA
FAU - de Rissio, A M
AU  - de Rissio AM
FAU - Marteleur, A
AU  - Marteleur A
FAU - Segura, E L
AU  - Segura EL
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Argentina
TA  - Medicina (B Aires)
JT  - Medicina
JID - 0204271
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Argentina/epidemiology
MH  - Chagas Disease/diagnosis/*epidemiology/transmission
MH  - Child
MH  - Child, Preschool
MH  - Electrocardiography
MH  - Female
MH  - Humans
MH  - Incidence
MH  - Infant
MH  - Male
MH  - Middle Aged
MH  - Rural Health
MH  - Serologic Tests/methods
EDAT- 1989/01/01 00:00
MHDA- 1989/01/01 00:01
CRDT- 1989/01/01 00:00
PHST- 1989/01/01 00:00 [pubmed]
PHST- 1989/01/01 00:01 [medline]
PHST- 1989/01/01 00:00 [entrez]
PST - ppublish
SO  - Medicina (B Aires). 1989;49(4):341-50.