PMID- 25188495
OWN - NLM
STAT- MEDLINE
DCOM- 20141023
LR  - 20211021
IS  - 1545-861X (Electronic)
IS  - 0149-2195 (Print)
IS  - 0149-2195 (Linking)
VI  - 63
IP  - 35
DP  - 2014 Sep 5
TI  - Fatal meningococcal disease in a laboratory worker--California, 2012.
PG  - 770-2
AB  - Occupationally acquired meningococcal disease is rare. Adherence to 
      recommendations for safe handling of Neisseria meningitidis in the laboratory 
      greatly reduces the risk for transmission to laboratory workers. A California 
      microbiologist developed fatal serogroup B meningococcal disease after working 
      with N. meningitidis patient isolates in a research laboratory (laboratory A). 
      The California Department of Public Health (CDPH), the local health department, 
      the California Division of Occupational Safety and Health (CalOSHA), and the 
      federal Occupational Safety and Health Administration (OSHA) collaborated on an 
      investigation of laboratory A, which revealed several breaches in recommended 
      laboratory practice for safe handling of N. meningitidis, including manipulating 
      cultures on the bench top. Additionally, laboratory workers had not been offered 
      meningococcal vaccine in accordance with Advisory Committee on Immunization 
      Practices (ACIP) recommendations and CalOSHA Aerosol Transmissible Diseases 
      Standard requirements. In accordance with OSHA and CalOSHA regulations, 
      laboratory staff members must receive laboratory biosafety training and use 
      appropriate personal protective equipment, and those who routinely work with N. 
      meningitidis isolates should receive meningococcal vaccine.
FAU - Sheets, Channing D
AU  - Sheets CD
FAU - Harriman, Kathleen
AU  - Harriman K
FAU - Zipprich, Jennifer
AU  - Zipprich J
FAU - Louie, Janice K
AU  - Louie JK
FAU - Probert, William S
AU  - Probert WS
FAU - Horowitz, Michael
AU  - Horowitz M
FAU - Prudhomme, Janice C
AU  - Prudhomme JC
FAU - Gold, Deborah
AU  - Gold D
FAU - Mayer, Leonard
AU  - Mayer L
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - MMWR Morb Mortal Wkly Rep
JT  - MMWR. Morbidity and mortality weekly report
JID - 7802429
SB  - IM
MH  - Adult
MH  - California
MH  - Fatal Outcome
MH  - Humans
MH  - Laboratories
MH  - Male
MH  - Meningococcal Infections/*diagnosis
MH  - Neisseria meningitidis/*isolation & purification
MH  - Occupational Diseases/*diagnosis
PMC - PMC5779447
EDAT- 2014/09/05 06:00
MHDA- 2014/10/24 06:00
PMCR- 2014/09/05
CRDT- 2014/09/05 06:00
PHST- 2014/09/05 06:00 [entrez]
PHST- 2014/09/05 06:00 [pubmed]
PHST- 2014/10/24 06:00 [medline]
PHST- 2014/09/05 00:00 [pmc-release]
AID - mm6335a2 [pii]
AID - 770-772 [pii]
PST - ppublish
SO  - MMWR Morb Mortal Wkly Rep. 2014 Sep 5;63(35):770-2.