PMID- 25194428 OWN - NLM STAT- MEDLINE DCOM- 20160525 LR - 20220409 IS - 1720-8386 (Electronic) IS - 0391-4097 (Linking) VI - 38 IP - 2 DP - 2015 Feb TI - Effectiveness of chamomile tea on glycemic control and serum lipid profile in patients with type 2 diabetes. PG - 163-70 LID - 10.1007/s40618-014-0170-x [doi] AB - AIMS: This study aimed at assessing the effects of chamomile tea consumption on glycemic control and serum lipid profile in patients with type 2 diabetes mellitus (T2DM). METHODS: This single-blind randomized controlled clinical trial was conducted on 64 individuals with T2DM (males and females) aged between 30 and 60 years. The intervention group (n = 32) consumed chamomile tea (3 g/150 mL hot water) three times per day immediately after meals for 8 weeks. The control group (n = 32) followed a water regimen for the same intervention period. Fasting blood samples, anthropometric measurements, and 3-day, 24-h dietary recalls were collected at the baseline and at the end of the trial. Data were analyzed by independent t test, paired t test, Pearson correlation test, and analysis of covariance. RESULTS: Chamomile tea significantly decreased concentration of HbA1C (p = 0.03), serum insulin levels (p < 0.001), homeostatic model assessment for insulin resistance (p < 0.001), total cholesterol (p = 0.001), triglyceride (p < 0.001), and low-density lipoprotein cholesterol (p = 0.05) compared with control group. No significant changes were shown in serum high-density lipoprotein cholesterol levels in both groups. CONCLUSION: Chamomile tea has some beneficial effects on glycemic control and serum lipid profile in T2DM patients. FAU - Rafraf, M AU - Rafraf M AD - Department of Nutrition in Community, Faculty of Nutrition, Nutrition Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. FAU - Zemestani, M AU - Zemestani M AD - Students' Research Committee, Faculty of Nutrition, Tabriz University of Medical Sciences, Tabriz, Iran. maryam.zemestani@yahoo.com. FAU - Asghari-Jafarabadi, M AU - Asghari-Jafarabadi M AD - Department of Statistics and Epidemiology, Faculty of Health, Tabriz Health Service Management Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. LA - eng PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't DEP - 20140907 PL - Italy TA - J Endocrinol Invest JT - Journal of endocrinological investigation JID - 7806594 RN - 0 (Blood Glucose) RN - 0 (Cholesterol, LDL) RN - 0 (Lipids) RN - 0 (Tea) RN - 0 (Triglycerides) RN - 97C5T2UQ7J (Cholesterol) SB - IM MH - Adult MH - Blood Glucose/*metabolism MH - *Chamomile MH - Cholesterol/blood MH - Cholesterol, LDL/blood MH - Diabetes Mellitus, Type 2/*blood/diagnosis/*diet therapy MH - Female MH - Follow-Up Studies MH - Glycemic Index/drug effects/physiology MH - Humans MH - Lipids/*blood MH - Male MH - Middle Aged MH - Single-Blind Method MH - *Tea MH - Treatment Outcome MH - Triglycerides/blood OTO - NOTNLM OT - Chamomile OT - Glycemic control OT - Serum lipids OT - Type 2 diabetes mellitus EDAT- 2014/09/10 06:00 MHDA- 2016/05/26 06:00 CRDT- 2014/09/08 06:00 PHST- 2014/07/08 00:00 [received] PHST- 2014/08/21 00:00 [accepted] PHST- 2014/09/08 06:00 [entrez] PHST- 2014/09/10 06:00 [pubmed] PHST- 2016/05/26 06:00 [medline] AID - 10.1007/s40618-014-0170-x [pii] AID - 10.1007/s40618-014-0170-x [doi] PST - ppublish SO - J Endocrinol Invest. 2015 Feb;38(2):163-70. doi: 10.1007/s40618-014-0170-x. Epub 2014 Sep 7.