PMID- 25201461
OWN - NLM
STAT- MEDLINE
DCOM- 20150720
LR  - 20211021
IS  - 1573-2584 (Electronic)
IS  - 0301-1623 (Linking)
VI  - 46
IP  - 12
DP  - 2014 Dec
TI  - Incidence and mortality of acute kidney injury in acute myocardial infarction 
      patients: a comparison between AKIN and RIFLE criteria.
PG  - 2371-7
LID - 10.1007/s11255-014-0827-6 [doi]
AB  - PURPOSE: Acute kidney injury (AKI) is associated with adverse outcomes after 
      acute ST elevation myocardial infarction (STEMI). The recently proposed AKI 
      network (AKIN) suggested modifications to the consensus classification system for 
      AKI known as the risk, injury, failure, loss, end-stage (RIFLE) criteria. The aim 
      of the current study was to compare the incidence and mortality (early and late) 
      of AKI diagnosed by RIFLE and AKIN criteria in the STEMI patients undergoing 
      primary percutaneous intervention (PCI). METHODS: We retrospectively studied 
      1,033 consecutive STEMI patients undergoing primary PCI. Recruited patients were 
      admitted between January 2008 and November 2012 to the cardiac intensive care 
      unit with the diagnosis of acute STEMI. We compared the utilization of RIFLE and 
      AKIN criteria for the diagnosis, classification, and prediction of mortality. 
      RESULTS: The AKIN criteria allowed the identification of more patients as having 
      AKI (9.6 vs. 3.9 %, p < 0.001) and classified more patients with stage 1 (risk in 
      RIFLE) (7.6 vs. 1.9 %, p < 0.001) compared with the RIFLE criteria. Mortality was 
      higher in AKI population defined by either RIFLE (46.3 vs. 6.8 %, OR 11.9, 95 % 
      CI 6.15-23.1; p < 0.001) or AKIN (29 vs. 6.1 %; OR 6.3, 95 % CI 3.8-10.4; p < 
      0.001) criteria. In a multivariable logistic regression model, AKI defined with 
      both RIFLE and AKIN was an independent predictor of both 30-day and up to 5-year 
      all-cause mortality. However, there was no significant statistical difference in 
      the risk provided by these two scoring systems. CONCLUSIONS: AKIN criteria are 
      more sensitive in defining AKI compared with the RIFLE criteria in STEMI. 
      However, no difference exists in the mortality risk provided by these two scoring 
      systems.
FAU - Shacham, Yacov
AU  - Shacham Y
AD  - Department of Cardiology, Tel-Aviv Sourasky Medical Center Affiliated to the 
      Sackler Faculty of Medicine, Tel-Aviv University, 6 Weizman Street, 64239, Tel 
      Aviv, Israel, kobyshacham@gmail.com.
FAU - Leshem-Rubinow, Eran
AU  - Leshem-Rubinow E
FAU - Ziv-Baran, Tomer
AU  - Ziv-Baran T
FAU - Gal-Oz, Amir
AU  - Gal-Oz A
FAU - Steinvil, Arie
AU  - Steinvil A
FAU - Ben Assa, Eyal
AU  - Ben Assa E
FAU - Keren, Gad
AU  - Keren G
FAU - Roth, Arie
AU  - Roth A
FAU - Arbel, Yaron
AU  - Arbel Y
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20140909
PL  - Netherlands
TA  - Int Urol Nephrol
JT  - International urology and nephrology
JID - 0262521
RN  - 0 (Biomarkers)
RN  - AYI8EX34EU (Creatinine)
SB  - IM
MH  - Acute Kidney Injury/*etiology/*mortality
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Biomarkers/blood
MH  - Creatinine/blood
MH  - Female
MH  - Glomerular Filtration Rate
MH  - Humans
MH  - Incidence
MH  - Male
MH  - Middle Aged
MH  - Myocardial Infarction/*complications/*surgery
MH  - Predictive Value of Tests
MH  - Retrospective Studies
EDAT- 2014/09/10 06:00
MHDA- 2015/07/21 06:00
CRDT- 2014/09/10 06:00
PHST- 2014/06/15 00:00 [received]
PHST- 2014/08/23 00:00 [accepted]
PHST- 2014/09/10 06:00 [entrez]
PHST- 2014/09/10 06:00 [pubmed]
PHST- 2015/07/21 06:00 [medline]
AID - 10.1007/s11255-014-0827-6 [doi]
PST - ppublish
SO  - Int Urol Nephrol. 2014 Dec;46(12):2371-7. doi: 10.1007/s11255-014-0827-6. Epub 
      2014 Sep 9.