PMID- 25219377
OWN - NLM
STAT- MEDLINE
DCOM- 20150605
LR  - 20211021
IS  - 1872-7972 (Electronic)
IS  - 0304-3940 (Print)
IS  - 0304-3940 (Linking)
VI  - 583
DP  - 2014 Nov 7
TI  - Tracheosyringeal nerve transection in juvenile male zebra finches decreases BDNF 
      in HVC and RA and the projection between them.
PG  - 26-31
LID - S0304-3940(14)00741-1 [pii]
LID - 10.1016/j.neulet.2014.09.014 [doi]
AB  - This study investigated relationships among disruption of normal vocal learning, 
      brain-derived neurotrophic factor (BDNF), and the morphology of song nuclei in 
      juvenile male zebra finches. The tracheosyringeal nerves were bilaterally 
      transected at post-hatching day 20-25, so that the animals could not properly 
      develop species-typical vocalizations. BDNF protein and the projection from HVC 
      to the robust nucleus of the arcopallium (RA) were quantified during the 
      sensorimotor integration phase of song development. The manipulation decreased 
      the number of BDNF cells in HVC and RA, the volume of these areas defined by BDNF 
      labeling, and the projection from HVC to RA. BDNF was not affected in Area X or 
      the lateral magnocellular nucleus of the anterior nidopallium (LMAN). Thus, 
      inhibition of a bird's ability to practice and/or to hear its own typically 
      developing song specifically diminishes BDNF expression in cortical motor regions 
      required for song production.
CI  - Copyright (c) 2014 Elsevier Ireland Ltd. All rights reserved.
FAU - Tang, Yu Ping
AU  - Tang YP
AD  - Michigan State University, Department of Psychology, East Lansing, MI 48824, 
      United States; Michigan State University, Neuroscience Program, East Lansing, MI 
      48824, United States. Electronic address: tangyupi@msu.edu.
FAU - Wade, Juli
AU  - Wade J
AD  - Michigan State University, Department of Psychology, East Lansing, MI 48824, 
      United States; Michigan State University, Department of Zoology, East Lansing, MI 
      48824, United States; Michigan State University, Neuroscience Program, East 
      Lansing, MI 48824, United States.
LA  - eng
GR  - R01 MH096705/MH/NIMH NIH HHS/United States
GR  - R01-MH096705/MH/NIMH NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
DEP - 20140916
PL  - Ireland
TA  - Neurosci Lett
JT  - Neuroscience letters
JID - 7600130
RN  - 0 (Brain-Derived Neurotrophic Factor)
SB  - IM
MH  - Animals
MH  - Brain-Derived Neurotrophic Factor/*metabolism
MH  - Efferent Pathways/metabolism
MH  - Finches/*physiology
MH  - High Vocal Center/*metabolism
MH  - Male
MH  - Peripheral Nerves/*physiology
MH  - Prosencephalon/*metabolism
MH  - Trachea/innervation
MH  - *Vocalization, Animal
PMC - PMC4253072
MID - NIHMS627829
OTO - NOTNLM
OT  - Motor system
OT  - Neurotrophin
OT  - Sexual differentiation
OT  - Song system
EDAT- 2014/09/16 06:00
MHDA- 2015/06/06 06:00
PMCR- 2015/11/07
CRDT- 2014/09/16 06:00
PHST- 2014/07/25 00:00 [received]
PHST- 2014/08/27 00:00 [revised]
PHST- 2014/09/04 00:00 [accepted]
PHST- 2014/09/16 06:00 [entrez]
PHST- 2014/09/16 06:00 [pubmed]
PHST- 2015/06/06 06:00 [medline]
PHST- 2015/11/07 00:00 [pmc-release]
AID - S0304-3940(14)00741-1 [pii]
AID - 10.1016/j.neulet.2014.09.014 [doi]
PST - ppublish
SO  - Neurosci Lett. 2014 Nov 7;583:26-31. doi: 10.1016/j.neulet.2014.09.014. Epub 2014 
      Sep 16.