PMID- 25219937 OWN - NLM STAT- MEDLINE DCOM- 20150929 LR - 20141203 IS - 1873-7862 (Electronic) IS - 0924-977X (Linking) VI - 24 IP - 11 DP - 2014 Nov TI - Equipercentile linking of scales measuring functioning and symptoms: examining the GAF, SOFAS, CGI-S, and PANSS. PG - 1767-72 LID - S0924-977X(14)00243-0 [pii] LID - 10.1016/j.euroneuro.2014.08.009 [doi] AB - The Global Assessment of Functioning (GAF) and the Social and Occupational Functioning Assessment Scale (SOFAS) are rating scales commonly used to assess the level of functioning in patients with schizophrenia. To understand the correspondence of scores between GAF and SOFAS, and what they mean from a clinical point of view, we examined the linkage of (a) GAF with SOFAS total scores, (b) GAF with Clinical Global Impressions Scale (CGI) and Positive and Negative Syndrome Scale (PANSS), and (c) SOFAS with CGI and PANSS. We used the equipercentile linking method to identify corresponding scores of simultaneous GAF, SOFAS, PANSS and CGI ratings in 1208 patients from a naturalistic European cohort study. Data were collected at baseline and at months 6, 12, 18 and 24. GAF and SOFAS total scores were found to be practically exchangeable. Both scales had strong negative correlations with CGI and PANSS; the linkage also suggested the presence of slight impairment in functioning even when patients are free from symptoms. These findings are important for the comparison of scores when different rating scales are used. We present a detailed conversion table in an online supplement. CI - Copyright (c) 2014 Elsevier B.V. and ECNP. All rights reserved. FAU - Samara, Myrto T AU - Samara MT AD - Department of Psychiatry and Psychotherapy, Technische Universitat Munchen, Klinikum rechts der Isar, Ismaningerstr. 22, 81675 Munich, Germany. FAU - Engel, Rolf R AU - Engel RR AD - Psychiatrische Klinik der Ludwig-Maximilian-Universitat Munchen, Nussbaumstrasse 7, 80336 Munich, Germany. FAU - Millier, Aurelie AU - Millier A AD - Creativ-Ceutical, 215 rue du Faubourg St-Honore, 75008 Paris, France. FAU - Kandenwein, Julia AU - Kandenwein J AD - Medical Therapeutic Area Lead Neuroscience and Rheumatology, Roche Pharma AG, Medical Management Specialty Care, Emil-Barell-Str.1, 79639 Grenzach-Wyhlen, Bau 200, 3-N.10, Germany. FAU - Toumi, Mondher AU - Toumi M AD - Aix Marseille University, Faculte de Medecine, Laboratoire de Sante Publique, 27 bd Jean Moulin, 13385 Marseille Cedex 05, France. FAU - Leucht, Stefan AU - Leucht S AD - Department of Psychiatry and Psychotherapy, Technische Universitat Munchen, Klinikum rechts der Isar, Ismaningerstr. 22, 81675 Munich, Germany. Electronic address: Stefan.Leucht@lrz.tum.de. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20140820 PL - Netherlands TA - Eur Neuropsychopharmacol JT - European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology JID - 9111390 SB - IM MH - Adult MH - Cohort Studies MH - Female MH - Humans MH - Male MH - *Psychiatric Status Rating Scales MH - Psychometrics MH - Schizophrenia/*diagnosis MH - Young Adult OTO - NOTNLM OT - Equipercentile OT - Functioning OT - GAF OT - Linking OT - SOFAS OT - Schizophrenia EDAT- 2014/09/16 06:00 MHDA- 2015/09/30 06:00 CRDT- 2014/09/16 06:00 PHST- 2014/07/08 00:00 [received] PHST- 2014/08/11 00:00 [revised] PHST- 2014/08/13 00:00 [accepted] PHST- 2014/09/16 06:00 [entrez] PHST- 2014/09/16 06:00 [pubmed] PHST- 2015/09/30 06:00 [medline] AID - S0924-977X(14)00243-0 [pii] AID - 10.1016/j.euroneuro.2014.08.009 [doi] PST - ppublish SO - Eur Neuropsychopharmacol. 2014 Nov;24(11):1767-72. doi: 10.1016/j.euroneuro.2014.08.009. Epub 2014 Aug 20.