PMID- 25220187
OWN - NLM
STAT- MEDLINE
DCOM- 20150714
LR  - 20141201
IS  - 1531-4332 (Electronic)
IS  - 1095-6433 (Linking)
VI  - 179
DP  - 2015 Jan
TI  - Kisspeptin regulates the somatic growth-related factors of the cinnamon clownfish 
      Amphiprion melanopus.
PG  - 17-24
LID - S1095-6433(14)00182-2 [pii]
LID - 10.1016/j.cbpa.2014.08.020 [doi]
AB  - This study aimed to test the effects of kisspeptin (Kiss) on somatic growth in 
      the cinnamon clownfish Amphiprion melanopus. We investigated the effects of Kiss 
      treatment on the growth by measuring the mRNA expressions of the growth hormone 
      (GH), insulin-like growth hormone factor (IGF-I), somatolactin (SL), and 
      melatonin receptor (MT). The expression levels of GH and SL of the pituitary 
      gland and IGF-I of the liver increased after Kiss treatment (in vivo and in 
      vitro). In addition, the MT mRNA expression increased in the pituitary gland and 
      brain after Kiss treatment (in vivo and in vitro). These results support the 
      hypothesis that Kiss directly regulates the somatic growth-related factors, such 
      as GH, SL, and MT, and IGF-I in the cinnamon clownfish. Further, injection of 
      Kiss resulted in significantly higher levels of plasma melatonin than that in the 
      control. We, therefore, conclude that Kiss plays a role in modulating growth and 
      artificially induced rapid growth in cinnamon clownfish.
CI  - Copyright (c) 2014 Elsevier Inc. All rights reserved.
FAU - Kim, Na Na
AU  - Kim NN
AD  - Division of Marine Environment & BioScience, Korea Maritime and Ocean University, 
      Busan 606-791, Republic of Korea.
FAU - Choi, Young-Ung
AU  - Choi YU
AD  - Korea Institute of Ocean Science & Technology, Ansan P.O. Box 29, 426-744, 
      Republic of Korea.
FAU - Park, Heung-Sik
AU  - Park HS
AD  - Korea Institute of Ocean Science & Technology, Ansan P.O. Box 29, 426-744, 
      Republic of Korea.
FAU - Choi, Cheol Young
AU  - Choi CY
AD  - Division of Marine Environment & BioScience, Korea Maritime and Ocean University, 
      Busan 606-791, Republic of Korea. Electronic address: choic@kmou.ac.kr.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20140915
PL  - United States
TA  - Comp Biochem Physiol A Mol Integr Physiol
JT  - Comparative biochemistry and physiology. Part A, Molecular & integrative 
      physiology
JID - 9806096
RN  - 0 (Fish Proteins)
RN  - 0 (Glycoproteins)
RN  - 0 (Intercellular Signaling Peptides and Proteins)
RN  - 0 (Kisspeptins)
RN  - 0 (Pituitary Hormones)
RN  - 0 (RNA, Messenger)
RN  - 0 (Receptors, Melatonin)
RN  - 0 (somatolactin protein, fish)
RN  - 67763-96-6 (Insulin-Like Growth Factor I)
RN  - 9002-72-6 (Growth Hormone)
RN  - JL5DK93RCL (Melatonin)
SB  - IM
MH  - Animals
MH  - Fish Proteins/genetics/metabolism
MH  - Gene Expression Regulation/drug effects
MH  - Glycoproteins/genetics/metabolism
MH  - Growth Hormone/genetics/metabolism
MH  - Insulin-Like Growth Factor I/genetics/metabolism
MH  - Intercellular Signaling Peptides and Proteins/*metabolism
MH  - Kisspeptins/*pharmacology
MH  - Liver/metabolism
MH  - Melatonin/genetics/metabolism
MH  - Perciformes/anatomy & histology/*growth & development
MH  - Pituitary Gland/cytology/drug effects/metabolism
MH  - Pituitary Hormones/genetics/metabolism
MH  - RNA, Messenger/genetics/metabolism
MH  - Receptors, Melatonin/metabolism
MH  - Time Factors
OTO - NOTNLM
OT  - Cinnamon clownfish
OT  - Growth hormone
OT  - Insulin-like growth factor I
OT  - Kisspeptin
OT  - Melatonin
OT  - Somatolactin
EDAT- 2014/09/16 06:00
MHDA- 2015/07/15 06:00
CRDT- 2014/09/16 06:00
PHST- 2014/05/29 00:00 [received]
PHST- 2014/07/31 00:00 [revised]
PHST- 2014/08/19 00:00 [accepted]
PHST- 2014/09/16 06:00 [entrez]
PHST- 2014/09/16 06:00 [pubmed]
PHST- 2015/07/15 06:00 [medline]
AID - S1095-6433(14)00182-2 [pii]
AID - 10.1016/j.cbpa.2014.08.020 [doi]
PST - ppublish
SO  - Comp Biochem Physiol A Mol Integr Physiol. 2015 Jan;179:17-24. doi: 
      10.1016/j.cbpa.2014.08.020. Epub 2014 Sep 15.