PMID- 25223905
OWN - NLM
STAT- MEDLINE
DCOM- 20160216
LR  - 20211021
IS  - 1872-6240 (Electronic)
IS  - 0006-8993 (Print)
IS  - 0006-8993 (Linking)
VI  - 1612
DP  - 2015 Jul 1
TI  - Age differences in self-referencing: Evidence for common and distinct encoding 
      strategies.
PG  - 118-27
LID - S0006-8993(14)01108-1 [pii]
LID - 10.1016/j.brainres.2014.08.033 [doi]
AB  - Although engagement of medial prefrontal cortex (MPFC) underlies self-referencing 
      of information for younger and older adults, the region has not consistently been 
      implicated across age groups for the encoding of self-referenced information. We 
      sought to determine whether making judgments about others as well as the self 
      influenced findings in the previous study. During an fMRI session, younger and 
      older adults encoded adjectives using only a self-reference task. For items later 
      remembered compared to those later forgotten, both age groups robustly recruited 
      medial prefrontal cortex, indicating common neural regions support encoding 
      across younger and older adults when participants make only self-reference 
      judgments. Focal age differences emerged in regions related to emotional 
      processing and cognitive control, though these differences are more limited than 
      in tasks in which judgments also are made about others. We conclude that making 
      judgments about another person differently affects the ways that younger and 
      older adults make judgments about the self, with results of a follow-up 
      behavioral study supporting this interpretation. This article is part of a 
      Special Issue entitled Memory and Aging.
CI  - Copyright (c) 2014 Elsevier B.V. All rights reserved.
FAU - Gutchess, Angela H
AU  - Gutchess AH
AD  - Brandeis University, Waltham, MA, USA; Athinoula A. Martinos Center, 
      Massachusetts General Hospital, Charlestown, MA, USA. Electronic address: 
      gutchess@brandeis.edu.
FAU - Sokal, Rebecca
AU  - Sokal R
AD  - Brandeis University, Waltham, MA, USA; University of Maryland School of Medicine, 
      Baltimore, MD, USA.
FAU - Coleman, Jennifer A
AU  - Coleman JA
AD  - Brandeis University, Waltham, MA, USA; Virginia Commonwealth University, 
      Richmond, VA, USA.
FAU - Gotthilf, Gina
AU  - Gotthilf G
AD  - Brandeis University, Waltham, MA, USA.
FAU - Grewal, Lauren
AU  - Grewal L
AD  - Brandeis University, Waltham, MA, USA; University of Pittsburgh, Pittsburgh, PA, 
      USA.
FAU - Rosa, Nicole
AU  - Rosa N
AD  - Brandeis University, Waltham, MA, USA; Harvard University, Cambridge, MA, USA.
LA  - eng
GR  - P41 RR014075/RR/NCRR NIH HHS/United States
GR  - R21 AG032382/AG/NIA NIH HHS/United States
GR  - R21AG032382/AG/NIA NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
DEP - 20140916
PL  - Netherlands
TA  - Brain Res
JT  - Brain research
JID - 0045503
RN  - S88TT14065 (Oxygen)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Age Factors
MH  - Aged
MH  - Aged, 80 and over
MH  - Aging/*physiology/*psychology
MH  - Analysis of Variance
MH  - Brain/anatomy & histology/blood supply/*physiology
MH  - Brain Mapping
MH  - Echo-Planar Imaging
MH  - Female
MH  - Humans
MH  - Image Processing, Computer-Assisted
MH  - Judgment
MH  - Magnetic Resonance Imaging
MH  - Male
MH  - Neuropsychological Tests
MH  - Oxygen/blood
MH  - Photic Stimulation
MH  - Recognition, Psychology/*physiology
MH  - *Self Concept
MH  - Vocabulary
MH  - Young Adult
PMC - PMC4362921
MID - NIHMS628283
OTO - NOTNLM
OT  - aging
OT  - fMRI
OT  - memory
OT  - self
EDAT- 2014/09/17 06:00
MHDA- 2016/02/18 06:00
PMCR- 2016/07/01
CRDT- 2014/09/17 06:00
PHST- 2014/05/09 00:00 [received]
PHST- 2014/08/09 00:00 [revised]
PHST- 2014/08/13 00:00 [accepted]
PHST- 2014/09/17 06:00 [entrez]
PHST- 2014/09/17 06:00 [pubmed]
PHST- 2016/02/18 06:00 [medline]
PHST- 2016/07/01 00:00 [pmc-release]
AID - S0006-8993(14)01108-1 [pii]
AID - 10.1016/j.brainres.2014.08.033 [doi]
PST - ppublish
SO  - Brain Res. 2015 Jul 1;1612:118-27. doi: 10.1016/j.brainres.2014.08.033. Epub 2014 
      Sep 16.