PMID- 25226339
OWN - NLM
STAT- MEDLINE
DCOM- 20161114
LR  - 20161230
IS  - 1558-2035 (Electronic)
IS  - 1558-2027 (Linking)
VI  - 17
IP  - 4
DP  - 2016 Apr
TI  - Correlation between trans and intra-thoracic impedance and conductance in 
      patients with chronic heart failure.
PG  - 276-82
LID - 10.2459/JCM.0000000000000177 [doi]
AB  - AIMS: In chronic heart failure, changes of intra-thoracic impedance (Z0IT) may 
      suggest impending pulmonary congestion; a similar result has been found by 
      measuring trans-thoracic conductance (TFCTT = 1/Z0 = 1/kOmega). We assumed that a 
      relationship could exist between Z0IT and TFCTT. METHODS: We collected 140 
      measurements from 70 patients carrying an implantable 
      cardioverter-defibrillator/cardiac resynchronization device with the CareLink 
      function (71 +/- 9 years, New York Heart Association (NYHA) 2.4 +/- 0.9, ejection 
      fraction 31 +/- 8%, optimal treatment); they were studied during system alarms and 
      after appropriate treatment (diuretics and/or vasodilators, n = 42) or during 
      clinical stability and at the time of a system alarm (n = 28); correspondent BNP 
      values were obtained. We related Z0IT obtained by the device, with TFCTT obtained 
      with a commercial system. RESULTS: A strong relationship was found between Z0IT 
      and TFCTT. Changes in the variables after treatment or during worsening 
      conditions were of the same direction and order of magnitude, and were related to 
      BNP levels obtained simultaneously. CONCLUSIONS: Trans-thoracic conductance, 
      similarly to intra-thoracic impedance, may noninvasively point to pulmonary 
      congestion and be useful in patients not carrying an implanted device. The 
      possibility of remotely obtaining this variable should be evaluated for the 
      telemonitoring of heart failure patients.
FAU - Malfatto, Gabriella
AU  - Malfatto G
AD  - aDivisione di Cardiologia, Ospedale San Luca, Istituto Auxologico Italiano IRCCS 
      bDipartimento di Medicina Clinica, Prevenzione e Biotecnologie Sanitarie, 
      Universita di Milano-Bicocca, Milan, Italy.
FAU - Villani, Alessandra
AU  - Villani A
FAU - Rosa, Francesco Della
AU  - Rosa FD
FAU - Rella, Valeria
AU  - Rella V
FAU - Oldani, Matteo
AU  - Oldani M
FAU - Giglio, Alessia
AU  - Giglio A
FAU - Facchini, Mario
AU  - Facchini M
FAU - Parati, Gianfranco
AU  - Parati G
LA  - eng
PT  - Journal Article
PT  - Observational Study
PL  - United States
TA  - J Cardiovasc Med (Hagerstown)
JT  - Journal of cardiovascular medicine (Hagerstown, Md.)
JID - 101259752
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Cardiography, Impedance
MH  - Chronic Disease
MH  - Defibrillators, Implantable
MH  - Electric Impedance
MH  - Female
MH  - Heart Failure/*physiopathology/therapy
MH  - Hemodynamics/physiology
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Monitoring, Physiologic/methods
MH  - Reproducibility of Results
MH  - Thoracic Cavity/physiopathology
EDAT- 2014/09/17 06:00
MHDA- 2016/11/15 06:00
CRDT- 2014/09/17 06:00
PHST- 2014/09/17 06:00 [entrez]
PHST- 2014/09/17 06:00 [pubmed]
PHST- 2016/11/15 06:00 [medline]
AID - 10.2459/JCM.0000000000000177 [doi]
PST - ppublish
SO  - J Cardiovasc Med (Hagerstown). 2016 Apr;17(4):276-82. doi: 
      10.2459/JCM.0000000000000177.