PMID- 25232411 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20140918 LR - 20211021 IS - 1940-5901 (Print) IS - 1940-5901 (Electronic) IS - 1940-5901 (Linking) VI - 7 IP - 8 DP - 2014 TI - Successful treatment of Kimura's disease with leflunomide and methylprednisolone: a case report. PG - 2219-22 AB - Kimura's disease (KD) is an uncommon, chronic inflammatory disease characterized by tumor-like lesions in the soft tissue and lymph nodes and increased peripheral blood eosinophil counts and serum immunoglobulin E (IgE). Prednisone is widely used to treat the disease. Here, we reported a 59-year-old KD patient failed to response to prednisone. Leflunomide combined with methylprednisolone (Medrol) were carried out to treat KD and encouraging outcome was obtained during the medication and 1 year follow up period. FAU - Ma, Xiao-Rong AU - Ma XR AD - Department of Plastic and Reconstructive Surgery, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine Shanghai, People's Republic of China. FAU - Xin, Shu-Jia AU - Xin SJ AD - Department of Nursing, Huadong Hospital, Shanghai Fudan University Shanghai, People's Republic of China. FAU - Ouyang, Tian-Xiang AU - Ouyang TX AD - Department of Plastic and Reconstructive Surgery, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine Shanghai, People's Republic of China. FAU - Ma, Yue-Ting AU - Ma YT AD - Department of Plastic and Reconstructive Surgery, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine Shanghai, People's Republic of China. FAU - Chen, Wei-Ying AU - Chen WY AD - Department of Rheumatology, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine Shanghai, People's Republic of China. FAU - Chang, Meng-Ling AU - Chang ML AD - Department of Plastic and Reconstructive Surgery, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine Shanghai, People's Republic of China. LA - eng PT - Journal Article DEP - 20140815 PL - United States TA - Int J Clin Exp Med JT - International journal of clinical and experimental medicine JID - 101471010 PMC - PMC4161571 OTO - NOTNLM OT - Kimura's disease OT - effect OT - eosinophilia OT - leflunomide EDAT- 2014/09/19 06:00 MHDA- 2014/09/19 06:01 PMCR- 2014/08/15 CRDT- 2014/09/19 06:00 PHST- 2014/07/01 00:00 [received] PHST- 2014/07/27 00:00 [accepted] PHST- 2014/09/19 06:00 [entrez] PHST- 2014/09/19 06:00 [pubmed] PHST- 2014/09/19 06:01 [medline] PHST- 2014/08/15 00:00 [pmc-release] PST - epublish SO - Int J Clin Exp Med. 2014 Aug 15;7(8):2219-22. eCollection 2014.