PMID- 25244652 OWN - NLM STAT- MEDLINE DCOM- 20150629 LR - 20141021 IS - 1399-0039 (Electronic) IS - 0001-2815 (Linking) VI - 84 IP - 5 DP - 2014 Nov TI - Unrelated donor HLA re-typing effort to verify prevalence of newer alleles: HLA-A*24:23, A*30:10, DRB1*08:11, DRB1*15:03, and DRB1*15:06. PG - 489-91 LID - 10.1111/tan.12442 [doi] AB - The National Marrow Donor Program (NMDP) is committed to maintaining accurate human leukocyte antigen (HLA) data for each of the 11.5 million volunteer donors on the Be The Match Registry((R)) . Qualitative data analysis identified five population specific alleles suspect of being incorrectly characterized. Alleles evaluated were HLA-A*24:03 for the presence of A*24:23 in Native Americans, A*30:02 for the presence of A*30:10 when B*41 and DRB1*04:05 were in the haplotype, DRB1*08:02 for the presence of DRB1*08:11 in Native Americans, and DRB1*15:01 for the presence of DRB1*15:03 in African Americans or DRB1*15:06 in Asian donors. Discrepancy rate was 55%, 86%, 31%, 75%, and 13%, respectively. Utilizing the HLA typing date, race, and date an allele in question was described may provide a selection strategy leading to the consideration of additional unrelated donors for searching patients. CI - (c) 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd. FAU - Kempenich, J AU - Kempenich J AD - National Marrow Donor Program, Scientific Services, Minneapolis, MN, USA. FAU - Dehn, J AU - Dehn J FAU - Flickinger, G AU - Flickinger G FAU - Setterholm, M AU - Setterholm M LA - eng PT - Journal Article DEP - 20140921 PL - England TA - Tissue Antigens JT - Tissue antigens JID - 0331072 RN - 0 (HLA-A Antigens) RN - 0 (HLA-A*30 antigen) RN - 0 (HLA-A24 Antigen) RN - 0 (HLA-DRB1 Chains) SB - IM MH - *Alleles MH - Databases, Nucleic Acid MH - Donor Selection MH - Female MH - HLA-A Antigens/*genetics MH - HLA-A24 Antigen/*genetics MH - HLA-DRB1 Chains/*genetics MH - Histocompatibility Testing MH - Humans MH - Male MH - Michigan MH - Registries MH - *Unrelated Donors OTO - NOTNLM OT - HLA-A OT - HLA-DRB1 OT - allele prevalence OT - sequence-based typing OT - stem cell OT - transplantation EDAT- 2014/09/23 06:00 MHDA- 2015/06/30 06:00 CRDT- 2014/09/23 06:00 PHST- 2014/03/19 00:00 [received] PHST- 2014/08/05 00:00 [revised] PHST- 2014/08/13 00:00 [accepted] PHST- 2014/09/23 06:00 [entrez] PHST- 2014/09/23 06:00 [pubmed] PHST- 2015/06/30 06:00 [medline] AID - 10.1111/tan.12442 [doi] PST - ppublish SO - Tissue Antigens. 2014 Nov;84(5):489-91. doi: 10.1111/tan.12442. Epub 2014 Sep 21.