PMID- 25247174 OWN - NLM STAT- MEDLINE DCOM- 20150615 LR - 20211021 IS - 2314-6141 (Electronic) IS - 2314-6133 (Print) VI - 2014 DP - 2014 TI - Function formula oriented construction of Bayesian inference nets for diagnosis of cardiovascular disease. PG - 376378 LID - 10.1155/2014/376378 [doi] LID - 376378 AB - An intelligent cardiovascular disease (CVD) diagnosis system using hemodynamic parameters (HDPs) derived from sphygmogram (SPG) signal is presented to support the emerging patient-centric healthcare models. To replicate clinical approach of diagnosis through a staged decision process, the Bayesian inference nets (BIN) are adapted. New approaches to construct a hierarchical multistage BIN using defined function formulas and a method employing fuzzy logic (FL) technology to quantify inference nodes with dynamic values of statistical parameters are proposed. The suggested methodology is validated by constructing hierarchical Bayesian fuzzy inference nets (HBFIN) to diagnose various heart pathologies from the deduced HDPs. The preliminary diagnostic results show that the proposed methodology has salient validity and effectiveness in the diagnosis of cardiovascular disease. FAU - Sekar, Booma Devi AU - Sekar BD AD - Department of ECE, Faculty of Science & Technology, University of Macau, Avenue Padre Tomas Pereira S.J.S, Macau. FAU - Dong, Mingchui AU - Dong M AD - Department of ECE, Faculty of Science & Technology, University of Macau, Avenue Padre Tomas Pereira S.J.S, Macau. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20140827 PL - United States TA - Biomed Res Int JT - BioMed research international JID - 101600173 SB - IM MH - Adolescent MH - Adult MH - Aged MH - Aged, 80 and over MH - Artificial Intelligence MH - *Bayes Theorem MH - Blood Pressure Determination/*methods MH - Cardiovascular Diseases/*diagnosis MH - Child, Preschool MH - Diagnosis, Computer-Assisted/*methods MH - Female MH - Humans MH - Infant MH - Infant, Newborn MH - Male MH - Middle Aged MH - *Neural Networks, Computer MH - Pattern Recognition, Automated/*methods MH - Reproducibility of Results MH - Sensitivity and Specificity MH - *Sphygmomanometers PMC - PMC4163461 EDAT- 2014/09/24 06:00 MHDA- 2015/06/16 06:00 PMCR- 2014/08/27 CRDT- 2014/09/24 06:00 PHST- 2014/02/06 00:00 [received] PHST- 2014/07/15 00:00 [revised] PHST- 2014/07/31 00:00 [accepted] PHST- 2014/09/24 06:00 [entrez] PHST- 2014/09/24 06:00 [pubmed] PHST- 2015/06/16 06:00 [medline] PHST- 2014/08/27 00:00 [pmc-release] AID - 10.1155/2014/376378 [doi] PST - ppublish SO - Biomed Res Int. 2014;2014:376378. doi: 10.1155/2014/376378. Epub 2014 Aug 27.