PMID- 25250300
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20140924
LR  - 20211021
IS  - 2277-9175 (Print)
IS  - 2277-9175 (Electronic)
IS  - 2277-9175 (Linking)
VI  - 3
DP  - 2014
TI  - Study of the possible medical and medication explanatory factors of angiographic 
      outcomes in patients with acute ST elevation myocardial infarction undergoing 
      primary percutaneous intervention.
PG  - 186
LID - 10.4103/2277-9175.140096 [doi]
LID - 186
AB  - BACKGROUND: Myocardial blush grade (MBG), thrombolysis in myocardial infarction 
      (TIMI) and corrected TIMI frame count (cTFC) are indices of successful 
      angiographic reperfusion. This study sought to determine the predictors of 
      angiographically successful reperfusion including demographic, clinical and 
      angiographic factors in patients with ST elevation myocardial infarction (STEMI) 
      undergoing primary percutaneous coronary intervention (pPCI). MATERIALS AND 
      METHODS: A cross-sectional study of patients with a confirmed diagnosis of STEMI 
      undergoing pPCI was designed. Eligible patients referring to a university heart 
      center were enrolled in the study from March 2012 to December 2012. Successful 
      epicardial reperfusion was defned as TIMI flow grade 3 or cTFC<= 28 frames and 
      successful myocardial reperfusion as MBG 2 or 3. RESULTS: The study population 
      consisted of 100 patients, including 74 males and 26 females, with mean +/- 
      standard deviation age of 58.27 +/- 11.60 years. Achieving open microvasculature 
      (MBG 2/3) was positively associated with a history of nitrate intake (P = 0.03) 
      and history of calcium channel blocker (CCB) intake (P = 0.005). Hyperglycemia 
      was inversely associated with achieving a final cTFC </= 28 frames (r = -0.32, P = 
      0.001). CONCLUSIONS: Our findings suggest that patients with a history of nitrate 
      and CCB intake had a higher likelihood of successful PCI. In addition, patients 
      with a higher blood glucose level on admission may have a reduced rate of 
      reperfusion success. Future studies with a larger sample size are recommended to 
      investigate the significant relationships observed in this study.
FAU - Eshraghi, Azadeh
AU  - Eshraghi A
AD  - Department of Clinical Pharmacy, School of Pharmacy, Shahid Beheshti, University 
      of Medical Sciences, Tehran, Iran ; Students Research Committee, Shahid Beheshti, 
      University of Medical Sciences, Tehran, Iran.
FAU - Talasaz, Azita Hajhossein
AU  - Talasaz AH
AD  - Department of Clinical Pharmacy, Faculty of Pharmacy, Tehran University of 
      Medical Sciences, Tehran, Iran ; Department of cardiology, Tehran Heart Center, 
      Tehran University of Medical Sciences, Tehran, Iran.
FAU - Salamzadeh, Jamshid
AU  - Salamzadeh J
AD  - Department of Clinical Pharmacy, School of Pharmacy, Shahid Beheshti, University 
      of Medical Sciences, Tehran, Iran.
FAU - Bahremand, Mostafa
AU  - Bahremand M
AD  - Kermanshah University of Medical Sciences, Kermanshah, Iran.
FAU - Salarifar, Mojtaba
AU  - Salarifar M
AD  - Department of cardiology, Tehran Heart Center, Tehran University of Medical 
      Sciences, Tehran, Iran.
FAU - Nozari, Yones
AU  - Nozari Y
AD  - Department of cardiology, Tehran Heart Center, Tehran University of Medical 
      Sciences, Tehran, Iran.
FAU - Jenab, Yaser
AU  - Jenab Y
AD  - Department of cardiology, Tehran Heart Center, Tehran University of Medical 
      Sciences, Tehran, Iran.
FAU - Boroumand, Mohammad Ali
AU  - Boroumand MA
AD  - Department of cardiology, Tehran Heart Center, Tehran University of Medical 
      Sciences, Tehran, Iran.
FAU - Vaseghi, Golnaz
AU  - Vaseghi G
AD  - Department of pharmacology, Applid Physiology Research Center, Isfahan University 
      of Medical Sciences, Isfahan, Iran.
FAU - Eshraghi, Nazanin
AU  - Eshraghi N
AD  - Department of Radiology, Tabriz University of Medical Science, Tabriz, Iran.
LA  - eng
PT  - Journal Article
DEP - 20140904
PL  - India
TA  - Adv Biomed Res
JT  - Advanced biomedical research
JID - 101586897
PMC - PMC4166209
OTO - NOTNLM
OT  - Corrected thrombolysis in myocardial infarction frame count
OT  - myocardial blush grade
OT  - outcome
OT  - risk factor
OT  - thrombolysis in myocardial infarction flow
COIS- Conflict of Interest: None declared.
EDAT- 2014/09/25 06:00
MHDA- 2014/09/25 06:01
PMCR- 2014/09/04
CRDT- 2014/09/25 06:00
PHST- 2013/06/19 00:00 [received]
PHST- 2013/09/08 00:00 [accepted]
PHST- 2014/09/25 06:00 [entrez]
PHST- 2014/09/25 06:00 [pubmed]
PHST- 2014/09/25 06:01 [medline]
PHST- 2014/09/04 00:00 [pmc-release]
AID - ABR-3-186 [pii]
AID - 10.4103/2277-9175.140096 [doi]
PST - epublish
SO  - Adv Biomed Res. 2014 Sep 4;3:186. doi: 10.4103/2277-9175.140096. eCollection 
      2014.