PMID- 25254248 OWN - NLM STAT- MEDLINE DCOM- 20150622 LR - 20231110 IS - 1537-744X (Electronic) IS - 2356-6140 (Print) IS - 1537-744X (Linking) VI - 2014 DP - 2014 TI - Cortical source multivariate EEG synchronization analysis on amnestic mild cognitive impairment in type 2 diabetes. PG - 523216 LID - 10.1155/2014/523216 [doi] LID - 523216 AB - Is synchronization altered in amnestic mild cognitive impairment (aMCI) and normal cognitive functions subjects in type 2 diabetes mellitus (T2DM)? Resting eye-closed EEG data were recorded in 8 aMCI subjects and 11 age-matched controls in T2DM. Three multivariate synchronization algorithms (S-estimator (S), synchronization index (SI), and global synchronization index (GSI)) were used to measure the synchronization in five ROIs of sLORETA sources for seven bands. Results showed that aMCI group had lower synchronization values than control groups in parietal delta and beta2 bands, temporal delta and beta2 bands, and occipital theta and beta2 bands significantly. Temporal (r = 0.629; P = 0.004) and occipital (r = 0.648; P = 0.003) theta S values were significantly positive correlated with Boston Name Testing. In sum, each of methods reflected that the cortical source synchronization was significantly different between aMCI and control group, and these difference correlated with cognitive functions. FAU - Cui, Dong AU - Cui D AUID- ORCID: 0000-0002-6468-1197 AD - School of Information Science and Engineering, Yanshan University, Qinhuangdao 066004, China. FAU - Liu, Jing AU - Liu J AUID- ORCID: 0000-0001-9549-0177 AD - School of Information Science and Engineering, Yanshan University, Qinhuangdao 066004, China. FAU - Bian, Zhijie AU - Bian Z AD - School of Electrical Engineering, Yanshan University, Qinhuangdao 066004, China. FAU - Li, Qiuli AU - Li Q AD - Department of Neurology, General Hospital of Second Artillery Corps of PLA, Beijing 100875, China. FAU - Wang, Lei AU - Wang L AD - Department of Neurology, General Hospital of Second Artillery Corps of PLA, Beijing 100875, China. FAU - Li, Xiaoli AU - Li X AD - School of Electrical Engineering, Yanshan University, Qinhuangdao 066004, China ; State Key Laboratory of Cognitive Neuroscience and Learning and IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing 100875, China ; Center for Collaboration and Innovation in Brain and Learning Sciences, Beijing Normal University, Beijing 100875, China ; National Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing 100875, China. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20140828 PL - United States TA - ScientificWorldJournal JT - TheScientificWorldJournal JID - 101131163 SB - IM MH - Aged MH - Aged, 80 and over MH - Algorithms MH - Beta Rhythm MH - Cerebral Cortex/*physiopathology MH - Cognitive Dysfunction/*physiopathology MH - *Cortical Synchronization MH - Delta Rhythm MH - Diabetes Mellitus, Type 2/*physiopathology MH - Female MH - Humans MH - Male MH - Middle Aged MH - Models, Neurological MH - Multivariate Analysis MH - Theta Rhythm PMC - PMC4164801 EDAT- 2014/09/26 06:00 MHDA- 2015/06/24 06:00 PMCR- 2014/08/28 CRDT- 2014/09/26 06:00 PHST- 2014/07/02 00:00 [received] PHST- 2014/08/14 00:00 [accepted] PHST- 2014/09/26 06:00 [entrez] PHST- 2014/09/26 06:00 [pubmed] PHST- 2015/06/24 06:00 [medline] PHST- 2014/08/28 00:00 [pmc-release] AID - 10.1155/2014/523216 [doi] PST - ppublish SO - ScientificWorldJournal. 2014;2014:523216. doi: 10.1155/2014/523216. Epub 2014 Aug 28.