PMID- 25255164
OWN - NLM
STAT- MEDLINE
DCOM- 20150909
LR  - 20211021
IS  - 1523-6536 (Electronic)
IS  - 1083-8791 (Print)
IS  - 1083-8791 (Linking)
VI  - 21
IP  - 2
DP  - 2015 Feb
TI  - Prevalence of chromosomally integrated human herpesvirus 6 in patients with human 
      herpesvirus 6-central nervous system dysfunction.
PG  - 371-3
LID - S1083-8791(14)00570-9 [pii]
LID - 10.1016/j.bbmt.2014.09.015 [doi]
AB  - We identified 37 hematopoietic cell transplantation recipients with human 
      herpesvirus 6 (HHV-6) central nervous system dysfunction and tested 
      donor-recipient pairs for chromosomally integrated HHV-6 (ciHHV-6). One patient 
      had ciHHV-6A with possible HHV-6A reactivation and encephalitis. There was no 
      ciHHV-6 enrichment in this group, but larger studies are needed to determine if 
      patients with ciHHV-6 are at increased risk for HHV-6-associated diseases or 
      other complications.
CI  - Copyright (c) 2015 American Society for Blood and Marrow Transplantation. Published 
      by Elsevier Inc. All rights reserved.
FAU - Hill, Joshua A
AU  - Hill JA
AD  - Division of Allergy and Infectious Diseases, University of Washington, Seattle, 
      Washington; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer 
      Research Center, Seattle, Washington. Electronic address: joshuaah@uw.edu.
FAU - Sedlak, Ruth Hall
AU  - Sedlak RH
AD  - Division of Laboratory Medicine, University of Washington, Seattle, Washington.
FAU - Zerr, Danielle M
AU  - Zerr DM
AD  - Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, 
      Seattle, Washington; Seattle Children's Research Institute, Seattle, Washington.
FAU - Huang, Meei-Li
AU  - Huang ML
AD  - Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, 
      Seattle, Washington.
FAU - Yeung, Cecilia
AU  - Yeung C
AD  - Department of Pathology, University of Washington, Seattle, Washington; Clinical 
      Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington.
FAU - Myerson, David
AU  - Myerson D
AD  - Department of Pathology, University of Washington, Seattle, Washington; Clinical 
      Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington.
FAU - Jerome, Keith R
AU  - Jerome KR
AD  - Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, 
      Seattle, Washington; Division of Laboratory Medicine, University of Washington, 
      Seattle, Washington.
FAU - Boeckh, Michael J
AU  - Boeckh MJ
AD  - Division of Allergy and Infectious Diseases, University of Washington, Seattle, 
      Washington; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer 
      Research Center, Seattle, Washington.
LA  - eng
GR  - K24 HL093294/HL/NHLBI NIH HHS/United States
GR  - P01 CA018029/CA/NCI NIH HHS/United States
GR  - HL093294/HL/NHLBI NIH HHS/United States
GR  - CA18029/CA/NCI NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
DEP - 20140922
PL  - United States
TA  - Biol Blood Marrow Transplant
JT  - Biology of blood and marrow transplantation : journal of the American Society for 
      Blood and Marrow Transplantation
JID - 9600628
RN  - 0 (DNA, Viral)
SB  - IM
MH  - Central Nervous System/metabolism/pathology/virology
MH  - Chromosomes, Human/chemistry/*virology
MH  - DNA, Viral/*cerebrospinal fluid
MH  - Encephalitis, Viral/cerebrospinal fluid/genetics/pathology/*virology
MH  - Hematopoietic Stem Cell Transplantation
MH  - Herpesvirus 6, Human/classification/*genetics/isolation & purification
MH  - Humans
MH  - Molecular Typing
MH  - Phylogeny
MH  - Roseolovirus Infections/cerebrospinal fluid/genetics/pathology/*virology
MH  - Transplantation, Homologous
MH  - Virus Activation
MH  - *Virus Integration
PMC - PMC4438705
MID - NIHMS686000
OTO - NOTNLM
OT  - Central nervous system (CNS)
OT  - Herpesvirus (hhv-6)
OT  - Integration
OT  - Transplant
EDAT- 2014/09/26 06:00
MHDA- 2015/09/10 06:00
PMCR- 2016/02/01
CRDT- 2014/09/26 06:00
PHST- 2014/07/17 00:00 [received]
PHST- 2014/09/15 00:00 [accepted]
PHST- 2014/09/26 06:00 [entrez]
PHST- 2014/09/26 06:00 [pubmed]
PHST- 2015/09/10 06:00 [medline]
PHST- 2016/02/01 00:00 [pmc-release]
AID - S1083-8791(14)00570-9 [pii]
AID - 10.1016/j.bbmt.2014.09.015 [doi]
PST - ppublish
SO  - Biol Blood Marrow Transplant. 2015 Feb;21(2):371-3. doi: 
      10.1016/j.bbmt.2014.09.015. Epub 2014 Sep 22.