PMID- 25261211
OWN - NLM
STAT- MEDLINE
DCOM- 20150608
LR  - 20211021
IS  - 1433-8491 (Electronic)
IS  - 0940-1334 (Linking)
VI  - 264 Suppl 1
DP  - 2014 Nov
TI  - Evidence-based psychotherapy for the prevention and treatment of first-episode 
      psychosis.
PG  - S17-25
LID - 10.1007/s00406-014-0538-0 [doi]
AB  - The aim of psychotherapy among individuals at clinical high risk (CHR) for 
      psychosis is to prevent transition to full-blown psychosis. Psychotherapy in 
      individuals with a first-episode psychosis (FEP) aims to reduce relapse rates. 
      Remission of (pre-) psychotic symptoms, psychosocial functioning, quality of 
      life, comorbid disorders and self-esteem are also important outcomes in 
      individuals at CHR and with FEP. Antipsychotics, Qmega-3-Fatty acids and 
      psychotherapy have been found to be effective in CHR for most of these aims. 
      Thereby psychotherapy presents a better benefit/risk ratio than antipsychotic 
      medication. The most evidence-based intervention is cognitive-behavioral therapy 
      (CBT). Psychotherapy is mostly offered to FEP patients within specialized early 
      intervention services (including assertiveness community treatment and 
      antipsychotic medication). Thereby, CBT is effective for positive symptoms and 
      family intervention is particularly effective for the prevention of relapses. We 
      introduce the principles of CBT for psychosis and suggest adaptions for 
      individuals at CHR and FEP. We conclude that the needs of young people at CHR and 
      with FEP are best met by specially designed, low threshold outpatient clinical 
      services, which include intensive psychotherapy treatment. A number of countries 
      have implemented early detection and intervention services based on this model, 
      while the implementation within in Germany is still marginal.
FAU - Muller, Hendrik
AU  - Muller H
AD  - Department of Psychiatry and Psychotherapy, University of Cologne, Cologne, 
      Germany.
FAU - Laier, Sonja
AU  - Laier S
FAU - Bechdolf, Andreas
AU  - Bechdolf A
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20140927
PL  - Germany
TA  - Eur Arch Psychiatry Clin Neurosci
JT  - European archives of psychiatry and clinical neuroscience
JID - 9103030
SB  - IM
MH  - *Evidence-Based Medicine
MH  - Humans
MH  - Psychotherapy/*methods
MH  - Psychotic Disorders/*prevention & control/*psychology
EDAT- 2014/09/28 06:00
MHDA- 2015/06/09 06:00
CRDT- 2014/09/28 06:00
PHST- 2014/08/14 00:00 [received]
PHST- 2014/09/07 00:00 [accepted]
PHST- 2014/09/28 06:00 [entrez]
PHST- 2014/09/28 06:00 [pubmed]
PHST- 2015/06/09 06:00 [medline]
AID - 10.1007/s00406-014-0538-0 [doi]
PST - ppublish
SO  - Eur Arch Psychiatry Clin Neurosci. 2014 Nov;264 Suppl 1:S17-25. doi: 
      10.1007/s00406-014-0538-0. Epub 2014 Sep 27.