PMID- 25262020
OWN - NLM
STAT- MEDLINE
DCOM- 20150715
LR  - 20141127
IS  - 1559-0720 (Electronic)
IS  - 0163-4984 (Linking)
VI  - 162
IP  - 1-3
DP  - 2014 Dec
TI  - Human health risks derived from dietary exposure to toxic metals in Catalonia, 
      Spain: temporal trend.
PG  - 26-37
LID - 10.1007/s12011-014-0138-x [doi]
AB  - The present study was aimed at estimating the current (2012) dietary intake of 
      arsenic (As), cadmium (Cd), mercury (Hg), and lead (Pb) by the population of 
      Catalonia, Spain. The temporal trends with respect to previous surveys, performed 
      in 2000, 2005, and 2008, were also determined. For that purpose, metal 
      concentrations were analyzed in a number of widely consumed foodstuffs. A 
      speciation study was also conducted by experimentally determining the levels of 
      inorganic As (InAs) and methylmercury (MeHg) in the same food items. Furthermore, 
      the dietary intake of those metals and species was calculated both 
      deterministically and probabilistically by considering two food consumption 
      surveys: ENCAT and ENIDE, representative of the Catalan and Spanish populations, 
      respectively. An important temporal decrease of the dietary intake was noted for 
      most elements, irrespective of the age-gender population group. Considering data 
      for a male adult, the current dietary intake of As, InAs, Cd, Hg, MeHg, and Pb 
      was estimated in 216, 2.6, 8.7, 10, 7.3, and 8.4 mug/day, respectively, being 
      these values lower than the respective provisional tolerable weekly intakes 
      (PTWIs) or benchmark dose lower confidence limits (BMDLs). Moreover, new 
      calculations by means of ENIDE survey indicated similar results to those 
      previously obtained by ENCAT, with the exception of MeHg, whose intake exceeded 
      the maximum recommended values for some part of the population. Although our data 
      are similar to those frequently found in other European countries, the important 
      intake of MeHg, which is linked to the high consumption of fish and shellfish, 
      deserves further investigation.
FAU - Perello, Gemma
AU  - Perello G
AD  - Laboratory of Toxicology and Environmental Health, School of Medicine, IISPV, 
      Universitat Rovira i Virgili, Sant Llorenc 21, 43201, Reus, Catalonia, Spain.
FAU - Llobet, Juan M
AU  - Llobet JM
FAU - Gomez-Catalan, Jesus
AU  - Gomez-Catalan J
FAU - Castell, Victoria
AU  - Castell V
FAU - Centrich, Francesc
AU  - Centrich F
FAU - Nadal, Marti
AU  - Nadal M
FAU - Domingo, Jose L
AU  - Domingo JL
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20140928
PL  - United States
TA  - Biol Trace Elem Res
JT  - Biological trace element research
JID - 7911509
RN  - 00BH33GNGH (Cadmium)
RN  - 2P299V784P (Lead)
RN  - FXS1BY2PGL (Mercury)
RN  - N712M78A8G (Arsenic)
SB  - IM
MH  - Arsenic/*toxicity
MH  - Cadmium/*toxicity
MH  - Food Contamination
MH  - Humans
MH  - Lead/*toxicity
MH  - Mercury/*toxicity
MH  - Spain
EDAT- 2014/09/30 06:00
MHDA- 2015/07/16 06:00
CRDT- 2014/09/29 06:00
PHST- 2014/09/08 00:00 [received]
PHST- 2014/09/22 00:00 [accepted]
PHST- 2014/09/29 06:00 [entrez]
PHST- 2014/09/30 06:00 [pubmed]
PHST- 2015/07/16 06:00 [medline]
AID - 10.1007/s12011-014-0138-x [doi]
PST - ppublish
SO  - Biol Trace Elem Res. 2014 Dec;162(1-3):26-37. doi: 10.1007/s12011-014-0138-x. 
      Epub 2014 Sep 28.