PMID- 2526624 OWN - NLM STAT- MEDLINE DCOM- 19890825 LR - 20090213 IS - 0003-9683 (Print) IS - 0003-9683 (Linking) VI - 82 IP - 3 DP - 1989 Mar TI - [Electric left ventricular hypertrophy and pulsatile component of arterial pressure in a population study]. PG - 299-303 AB - High systolic or diastolic blood pressure is a risk factor of left ventricular hypertrophy. However, haemodynamically speaking blood pressure is made of two components: continuous and pulsatile. Few authors have analysed the relationship between these two components and left ventricular hypertrophy. A horizontal study was conducted in 27, 687 subjects who volunteered for a medical check-up in Paris. A principal component analysis led to the estimation of two distinct parameters: a continuous pressure index (CPI) and a pulsed pressure index (PPI). The correlation between CPI and age was linear, whereas PPI was independent of age before 55 years and thereafter increased in a linear manner. This study also confirmed the importance of the relationship between the continuous component of blood pressure and electrocardiographic left ventricular hypertrophy. It is suggested that the pulsatile component might also be a risk factor of left ventricular hypertrophy independently of the continuous component level. Only a prospective study would confirm that an increase in the pulsatile component of blood pressure has a prognostic value as regards ventricular hypertrophy. FAU - Darne, B AU - Darne B AD - INSERM U 258, hopital Broussais, Paris. FAU - Girerd, X AU - Girerd X FAU - Safar, M AU - Safar M FAU - Guize, L AU - Guize L LA - fre PT - English Abstract PT - Journal Article PT - Research Support, Non-U.S. Gov't TT - Hypertrophie ventriculaire gauche electrique et composante pulsee de la pression arterielle dans une etude de population. PL - France TA - Arch Mal Coeur Vaiss JT - Archives des maladies du coeur et des vaisseaux JID - 0406011 SB - IM MH - Adult MH - Age Factors MH - Aged MH - *Blood Pressure MH - Cardiomegaly/*physiopathology MH - Cross-Sectional Studies MH - Electrocardiography MH - Female MH - France MH - Humans MH - Hypertension/*physiopathology MH - Male MH - Middle Aged MH - Risk Factors EDAT- 1989/03/01 00:00 MHDA- 1989/03/01 00:01 CRDT- 1989/03/01 00:00 PHST- 1989/03/01 00:00 [pubmed] PHST- 1989/03/01 00:01 [medline] PHST- 1989/03/01 00:00 [entrez] PST - ppublish SO - Arch Mal Coeur Vaiss. 1989 Mar;82(3):299-303.