PMID- 25267708 OWN - NLM STAT- MEDLINE DCOM- 20150224 LR - 20191210 IS - 1873-3778 (Electronic) IS - 0021-9673 (Linking) VI - 1366 DP - 2014 Oct 31 TI - Preparation and evaluation of silica-UIO-66 composite as liquid chromatographic stationary phase for fast and efficient separation. PG - 45-53 LID - S0021-9673(14)01342-9 [pii] LID - 10.1016/j.chroma.2014.08.077 [doi] AB - A silica-UIO-66 composite was fabricated by a simple hydrothermal method and then applied as liquid chromatographic stationary phase for fast and efficient separation. X-ray diffraction patterns showed the presence of UIO-66 crystals in the silica-UIO-66 composites; while scanning electron microscope (SEM) images revealed that silica-UIO-66 composites were a homogeneous mixture of silica bead and UIO-66 crystals. A variety of substituted aromatics, chlorobenzene compounds and polycyclic aromatic hydrocarbons (PAHs) were used to evaluate the retention properties of the silica-UIO-66 composite packed column. Under the optimized conditions, baseline separation of ethylbenzene (EB) and styrene was obtained with high resolution and short retention time. In addition, the silica-UIO-66 composite packed column also showed some advantages in separation of positional isomers, with which baseline separation of EB and xylene, chlorotoluene and dichlorobenzene isomers was achieved. Moreover, the retention mechanisms of these compounds were also discussed in detail. The relative standard deviations (RSDs) for the separation of EB and xylene, chlorotoluene and dichlorobenzene isomers, as well as EB and styrene were 0.42-0.9%, 1.0-1.9%, 0.75-2.0%, and 0.9-2.1% for the retention time, peak area, peak height, and half peak width, respectively. The column efficiencies for EB, p-chlorotoluene, p-dichlorobenzene and styrene were 8780, 9060, 9990 and 5130 plates/m. The successful applications suggested high potentials of silica-MOFs composite as stationary phase for fast and efficient liquid chromatography separation. CI - Copyright (c) 2014 Elsevier B.V. All rights reserved. FAU - Yan, Zhiming AU - Yan Z AD - Ministry of Education Key Laboratory of Analysis and Detection for Food Safety, Fujian Provincial Key Laboratory of Analysis and Detection Technology for Food Safety, College of Chemistry, Fuzhou University, Fuzhou, Fujian, 350116, China. FAU - Zheng, Jiangnan AU - Zheng J AD - Ministry of Education Key Laboratory of Analysis and Detection for Food Safety, Fujian Provincial Key Laboratory of Analysis and Detection Technology for Food Safety, College of Chemistry, Fuzhou University, Fuzhou, Fujian, 350116, China. FAU - Chen, Jinfeng AU - Chen J AD - Ministry of Education Key Laboratory of Analysis and Detection for Food Safety, Fujian Provincial Key Laboratory of Analysis and Detection Technology for Food Safety, College of Chemistry, Fuzhou University, Fuzhou, Fujian, 350116, China; Longyan Entry-Exit Inspection and Quarantine Bureau of P.R.C, Longyan/=, Fujian, 364000, China. FAU - Tong, Ping AU - Tong P AD - Ministry of Education Key Laboratory of Analysis and Detection for Food Safety, Fujian Provincial Key Laboratory of Analysis and Detection Technology for Food Safety, College of Chemistry, Fuzhou University, Fuzhou, Fujian, 350116, China; Testing Center, The Sport Science Research Center, Fuzhou University, Fuzhou, Fujian, 350002, China. FAU - Lu, Minghua AU - Lu M AD - Testing Center, The Sport Science Research Center, Fuzhou University, Fuzhou, Fujian, 350002, China. FAU - Lin, Zian AU - Lin Z AD - Ministry of Education Key Laboratory of Analysis and Detection for Food Safety, Fujian Provincial Key Laboratory of Analysis and Detection Technology for Food Safety, College of Chemistry, Fuzhou University, Fuzhou, Fujian, 350116, China. Electronic address: zianlin@fzu.edu.cn. FAU - Zhang, Lan AU - Zhang L AD - Ministry of Education Key Laboratory of Analysis and Detection for Food Safety, Fujian Provincial Key Laboratory of Analysis and Detection Technology for Food Safety, College of Chemistry, Fuzhou University, Fuzhou, Fujian, 350116, China; Testing Center, The Sport Science Research Center, Fuzhou University, Fuzhou, Fujian, 350002, China. Electronic address: zlan@fzu.edu.cn. LA - eng PT - Evaluation Study PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20140830 PL - Netherlands TA - J Chromatogr A JT - Journal of chromatography. A JID - 9318488 RN - 0 (Benzene Derivatives) RN - 0 (Chlorobenzenes) RN - 0 (Xylenes) RN - 3FPU23BG52 (Toluene) RN - 44LJ2U959V (Styrene) RN - 7631-86-9 (Silicon Dioxide) RN - D149TYB5MK (4-dichlorobenzene) RN - K18102WN1G (chlorobenzene) RN - L5I45M5G0O (ethylbenzene) RN - Q8R236H42N (4-chlorotoluene) SB - IM MH - Benzene Derivatives/chemistry MH - Chlorobenzenes/chemistry MH - Chromatography, Liquid/*instrumentation MH - Isomerism MH - Microscopy, Electron, Scanning MH - Silicon Dioxide/*chemistry MH - Styrene/chemistry MH - Toluene/analogs & derivatives/chemistry MH - X-Ray Diffraction MH - Xylenes/chemistry OTO - NOTNLM OT - Fast separation OT - High performance chromatography (HPLC) OT - Metal-organic frameworks (MOFs) OT - Positional isomers OT - Silica-UIO-66 composite EDAT- 2014/10/01 06:00 MHDA- 2015/02/25 06:00 CRDT- 2014/10/01 06:00 PHST- 2014/03/28 00:00 [received] PHST- 2014/08/07 00:00 [revised] PHST- 2014/08/26 00:00 [accepted] PHST- 2014/10/01 06:00 [entrez] PHST- 2014/10/01 06:00 [pubmed] PHST- 2015/02/25 06:00 [medline] AID - S0021-9673(14)01342-9 [pii] AID - 10.1016/j.chroma.2014.08.077 [doi] PST - ppublish SO - J Chromatogr A. 2014 Oct 31;1366:45-53. doi: 10.1016/j.chroma.2014.08.077. Epub 2014 Aug 30.