PMID- 25269267
OWN - NLM
STAT- MEDLINE
DCOM- 20150901
LR  - 20190923
IS  - 1000-8713 (Print)
IS  - 1000-8713 (Linking)
VI  - 32
IP  - 6
DP  - 2014 Jun
TI  - [Determination of urinary cotinine of children exposed to passive smoking by 
      stable isotope dilution gas chromatography-triple quadrupole mass spectrometry].
PG  - 658-61
AB  - An analytical method for the determination of urinary cotinine of children 
      exposed to passive smoking was established based on stable isotope dilution by 
      gas chromatography-triple quadrupole mass spectrometry (GC-MS/MS). The samples 
      were extracted and purified with chloroform. The extracts were determined by 
      GC-MS/MS in multiple reaction monitoring (MRM) mode. The cotinine-d3 as an 
      isotope internal standard was applied to quantify and confirm the urinary 
      cotinine of children exposed to passive smoking. The method had a good linearity 
      from 0.1 microg/L to 10 microg/L with the correlation coefficient (r) > 0.998. 
      The recoveries of the cotinine in blank urine were from 79.2% to 112.8% at spiked 
      levels of 0.1, 1.0 and 10 microg/ L, with relative standard deviations (RSDs) 
      from 2.1% to 5. 8%. The limit of quantification ( LOQ) of the method was 0.1 
      microg/L. The developed method is accurate, sensitive, rapid and can be applied 
      to detect urinary cotinine of children exposed to passive smoking at home.
FAU - Wang, Yun
AU  - Wang Y
FAU - Huang, Zhiqiang
AU  - Huang Z
FAU - Ye, Ying
AU  - Ye Y
FAU - Zhang, Ying
AU  - Zhang Y
FAU - Xiao, Shuiyuan
AU  - Xiao S
LA  - chi
PT  - Journal Article
PL  - China
TA  - Se Pu
JT  - Se pu = Chinese journal of chromatography
JID - 9424804
RN  - 0 (Isotopes)
RN  - 0 (Tobacco Smoke Pollution)
RN  - K5161X06LL (Cotinine)
SB  - IM
MH  - Child
MH  - Cotinine/*urine
MH  - Gas Chromatography-Mass Spectrometry
MH  - Humans
MH  - Isotopes
MH  - Tandem Mass Spectrometry
MH  - *Tobacco Smoke Pollution
EDAT- 2014/10/02 06:00
MHDA- 2015/09/02 06:00
CRDT- 2014/10/02 06:00
PHST- 2014/10/02 06:00 [entrez]
PHST- 2014/10/02 06:00 [pubmed]
PHST- 2015/09/02 06:00 [medline]
AID - 10.3724/sp.j.1123.2014.01023 [doi]
PST - ppublish
SO  - Se Pu. 2014 Jun;32(6):658-61. doi: 10.3724/sp.j.1123.2014.01023.