PMID- 25272960
OWN - NLM
STAT- MEDLINE
DCOM- 20151116
LR  - 20211021
IS  - 1572-994X (Electronic)
IS  - 0920-8569 (Linking)
VI  - 50
IP  - 1
DP  - 2015 Feb
TI  - Complete genomic characterization of a porcine reproductive and respiratory 
      syndrome virus isolate in Xinjiang province of China.
PG  - 39-45
LID - 10.1007/s11262-014-1122-4 [doi]
AB  - Porcine reproductive and respiratory syndrome (PRRS) is a swine disease of major 
      economic importance that causes reproductive and respiratory problems in pigs. In 
      the present study, one strain of porcine reproductive and respiratory syndrome 
      virus (PRRSV) was isolated in Xinjiang province, Northwest China, designated 
      XJu-1. The full-length genome of XJu-1 was found to be 14,987 nucleotides in 
      length, including the poly(A) tail. Comparative analysis with the genomic 
      sequences of type 2 isolates revealed that XJu-1 shared 87.2-99.2 % identity with 
      these isolates, but only 60.4 % with the type 1 virus-Lelystad Virus, indicating 
      that this new Chinese isolate was closely related to the North American PRRSV 
      genotype. XJu-1 was a novel strain with unique deletions in NSP2 region, namely 
      that 150-amino acid deletion in NSP2. The genomic variations of XJu-1 strain 
      provided the basis for further studies of virulence determinants and evolution 
      for PRRSVs.
FAU - Xia, Jun
AU  - Xia J
AD  - College of Animal Science, Shihezi University, Shihezi, 832003, People's Republic 
      of China.
FAU - Chen, Shijun
AU  - Chen S
FAU - Huang, Jion
AU  - Huang J
FAU - Ma, Wenge
AU  - Ma W
FAU - Du, Wei
AU  - Du W
FAU - Yang, Xueyun
AU  - Yang X
FAU - Liu, Yanfeng
AU  - Liu Y
FAU - Yan, Genqiang
AU  - Yan G
LA  - eng
SI  - GENBANK/KF815525
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20141002
PL  - United States
TA  - Virus Genes
JT  - Virus genes
JID - 8803967
RN  - 0 (RNA, Viral)
SB  - IM
MH  - Animals
MH  - China
MH  - Cluster Analysis
MH  - *Genome, Viral
MH  - Genotype
MH  - Molecular Sequence Data
MH  - Phylogeny
MH  - Porcine Reproductive and Respiratory Syndrome/*virology
MH  - Porcine respiratory and reproductive syndrome virus/*genetics/*isolation & 
      purification
MH  - RNA, Viral/*genetics
MH  - *Sequence Analysis, DNA
MH  - Sequence Homology, Amino Acid
MH  - Swine
EDAT- 2014/10/03 06:00
MHDA- 2015/11/17 06:00
CRDT- 2014/10/03 06:00
PHST- 2014/04/29 00:00 [received]
PHST- 2014/09/23 00:00 [accepted]
PHST- 2014/10/03 06:00 [entrez]
PHST- 2014/10/03 06:00 [pubmed]
PHST- 2015/11/17 06:00 [medline]
AID - 10.1007/s11262-014-1122-4 [doi]
PST - ppublish
SO  - Virus Genes. 2015 Feb;50(1):39-45. doi: 10.1007/s11262-014-1122-4. Epub 2014 Oct 
      2.