PMID- 25272986
OWN - NLM
STAT- MEDLINE
DCOM- 20151103
LR  - 20211021
IS  - 1433-0563 (Electronic)
IS  - 0340-2592 (Linking)
VI  - 53
IP  - 12
DP  - 2014 Dec
TI  - [Penis-preserving surgery in patients with primary penile urethral cancer].
PG  - 1800-4
LID - 10.1007/s00120-014-3583-4 [doi]
AB  - BACKGROUND: Primary urethral cancer in males is a rare entity with only 
      approximately 800 cases described, which is why it is difficult to formulate 
      evidence-based guidelines for treatment. For tumors in the pT2 stage with a 
      localization distal to the membranous urethra, a penis-preserving operation can 
      be carried out. METHODS: In the period from November 2006 to February 2014 a 
      total of 4 patients with primary urethral cancer underwent a penis-preserving 
      urethral resection. The tumor characteristics and treatment results were collated 
      retrospectively. RESULTS: Of the four patients one had a transitional cell 
      carcinoma of the mid-penile urethra in stage pT2 G2. In two out of the four 
      patients a squamous cell carcinoma (PEC) was present in the mid-penile urethra in 
      stages pT2 G2 and pT2 G3, respectively, with concomitant carcinoma in situ (CIS). 
      The fourth patient had a PEC of the fossa terminalis in stage pT2 G2. Initially 
      all patients underwent a penis-preserving resection. In one case, despite an 
      initial R0 resection a local recurrence occurred and a complete penectomy was 
      performed. Irradiation and lymphadenectomy were not carried out. At a mean 
      follow-up of 37 months all patients are currently in complete remission. 
      CONCLUSION: Primary penile urethral cancer can be treated by a penis-preserving 
      operation. Close follow-up is essential because recurrence can arise despite an 
      initial R0 resection.
FAU - Maek, M
AU  - Maek M
AD  - Kliniken Essen-Mitte, Henricistrasse 92, 45136, Essen, Deutschland, 
      m.maek@kliniken-essen-mitte.de.
FAU - Musch, M
AU  - Musch M
FAU - Arnold, G
AU  - Arnold G
FAU - Kropfl, D
AU  - Kropfl D
LA  - ger
PT  - Case Reports
PT  - English Abstract
PT  - Journal Article
TT  - Peniserhaltende Chirurgie beim primaren Harnrohrenkarzinom der penilen Urethra.
PL  - Germany
TA  - Urologe A
JT  - Der Urologe. Ausg. A
JID - 1304110
SB  - IM
EIN - Urologe A. 2014 Dec;53(12):1804. Musch, M [added]; Arnold, G [added]; Kropfl, D 
      [added]
MH  - Aged
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Minimally Invasive Surgical Procedures/methods
MH  - Organ Sparing Treatments/*methods
MH  - Penile Neoplasms/pathology/*surgery
MH  - Penis/pathology/*surgery
MH  - Treatment Outcome
MH  - Urethral Neoplasms/pathology/*surgery
MH  - Urologic Surgical Procedures, Male/*methods
EDAT- 2014/10/03 06:00
MHDA- 2015/11/04 06:00
CRDT- 2014/10/03 06:00
PHST- 2014/10/03 06:00 [entrez]
PHST- 2014/10/03 06:00 [pubmed]
PHST- 2015/11/04 06:00 [medline]
AID - 10.1007/s00120-014-3583-4 [doi]
PST - ppublish
SO  - Urologe A. 2014 Dec;53(12):1800-4. doi: 10.1007/s00120-014-3583-4.