PMID- 25273482
OWN - NLM
STAT- MEDLINE
DCOM- 20150609
LR  - 20220408
IS  - 1539-0829 (Electronic)
IS  - 1534-4827 (Linking)
VI  - 14
IP  - 11
DP  - 2014
TI  - Assessing premorbid cognitive ability in adults with type 2 diabetes mellitus--a 
      review with implications for future intervention studies.
PG  - 547
LID - 10.1007/s11892-014-0547-4 [doi]
AB  - Associations between type 2 diabetes mellitus (T2DM) and accelerated cognitive 
      decline are well established. However, the sensitivity of neuropsychological 
      tests to detect early deficits in cognitively normal adults with T2DM is unknown. 
      This review examined cognitive domains and specific neuropsychological tests that 
      are impaired in T2DM, based on clinically significant differences (effect sizes 
      >0.5) between T2DM and groups without T2DM. Nine cross-sectional studies were 
      identified which reported means and standard deviations for individual tests. 
      Tests of executive function, working memory and psychomotor and attentional 
      functions were found to be impaired in T2DM. Impairments of executive function 
      and choice reaction time may have consequences for everyday functioning, in 
      particular the risk of falls in older adults. More research on cognitive deficits 
      in dual-task situations and how they impact everyday functioning is needed; the 
      Trail Making Task, Symbol Digit Modalities Test, Verbal Fluency Task and tests of 
      reaction time and processing speed could be included as core components of test 
      batteries in future intervention studies. They could also be assessed in newly 
      diagnosed T2DM and used to monitor progressive deterioration of cognitive 
      function and the efficacy of therapeutic interventions on cognitive function.
FAU - Wong, Rachel Heloise Xiwen
AU  - Wong RH
AD  - Clinical Nutrition Research Centre, School of Biomedical Sciences and Pharmacy, 
      University of Newcastle, Callaghan, Newcastle, New South Wales, 2308, Australia, 
      Rachel.wong@newcastle.edu.au.
FAU - Scholey, Andrew
AU  - Scholey A
FAU - Howe, Peter Ranald Charles
AU  - Howe PR
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Curr Diab Rep
JT  - Current diabetes reports
JID - 101093791
SB  - IM
MH  - Adult
MH  - *Cognition
MH  - Cognition Disorders/*etiology/prevention & control/psychology
MH  - Cross-Sectional Studies
MH  - Diabetes Mellitus, Type 2/complications/physiopathology/*psychology
MH  - Disease Progression
MH  - Executive Function
MH  - Humans
MH  - Neuropsychological Tests
MH  - Psychomotor Performance
MH  - Task Performance and Analysis
MH  - Time Factors
EDAT- 2014/10/03 06:00
MHDA- 2015/06/10 06:00
CRDT- 2014/10/03 06:00
PHST- 2014/10/03 06:00 [entrez]
PHST- 2014/10/03 06:00 [pubmed]
PHST- 2015/06/10 06:00 [medline]
AID - 10.1007/s11892-014-0547-4 [doi]
PST - ppublish
SO  - Curr Diab Rep. 2014;14(11):547. doi: 10.1007/s11892-014-0547-4.