PMID- 25276964
OWN - NLM
STAT- MEDLINE
DCOM- 20141028
LR  - 20191210
IS  - 1001-5302 (Print)
IS  - 1001-5302 (Linking)
VI  - 39
IP  - 13
DP  - 2014 Jul
TI  - [Determination of myclobutanil 25% WG degradation dynamics in ginseng root, stem, 
      leaf and soil by HPLC-MS/MS].
PG  - 2464-8
AB  - A high performance liquid chromatography coupled with tandem mass spectrometry 
      (HPLC-MS/MS) method was developed for determining degradation dynamics and final 
      residues of myclobutanil 25% WG in ginseng root, stem, leaf and soil. The samples 
      were extracted with acetonitrile, cleaned-up with primary secondary amine (PSA) 
      solid phase extraction cartridge, separated by Kromasil Eternity-5-C18 (2.1 mm x 
      150 mm, 5 microm) column with a gradient of acetonitrile and 0.1% formate in 
      water as mobile phases, and analyzed with the multiple reaction monitoring (MRM) 
      in positive ion mode by employing the external standard method. The average 
      recoveries and the relative standard derivations (RSDs) of myclobutanil at the 
      spiked level of 0.01-0.20 mg x kg(-1) were 80.9%-90.7% and 5.54%-9.29%, 
      respectively, and the limit of quantification (LOQ) was 0.005 mg x kg(-1). The 
      method with good reproducible, high precision and low detection limit could meet 
      the requirements of residual analysis on ginseng production. The half-lives of 
      myclobutanil were from 6.25 days to 9.94 days in ginseng root, stem, leaf and 
      soil at spraying dosage of 1 152 g x hm(-2) The final residues were below 0.060 1 
      mg x kg(-1) in root, below 0.081 7 mg x kg(-1) in stem, 0.006 0-0.102 2 mg x 
      kg(-1) in leaf and below 0.037 6 mg x kg(-1) in soil at spraying dosage range 
      from 576 to 1 152 g x hm(-2). It is recommended that the MRLs of myclobutanil in 
      dried ginseng may be suggested to be 0.10 mg x kg(-1) temporarily, and the 
      preharvest interval was set at 35 days.
FAU - Wang, Yan
AU  - Wang Y
FAU - Wang, Chun-Wei
AU  - Wang CW
FAU - Gao, Jie
AU  - Gao J
FAU - Cui, Li-Li
AU  - Cui LL
FAU - Xu, Yun-Cheng
AU  - Xu YC
LA  - chi
PT  - Evaluation Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - China
TA  - Zhongguo Zhong Yao Za Zhi
JT  - Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese 
      materia medica
JID - 8913656
RN  - 0 (Fungicides, Industrial)
RN  - 0 (Nitriles)
RN  - 0 (Soil Pollutants)
RN  - 0 (Triazoles)
RN  - B6T1JTM6KZ (systhane)
SB  - IM
MH  - Chromatography, High Pressure Liquid/*methods
MH  - Drug Contamination
MH  - Fungicides, Industrial/*chemistry
MH  - Nitriles/*chemistry
MH  - Panax/*chemistry
MH  - Plant Leaves/chemistry
MH  - Plant Roots/chemistry
MH  - Plant Stems/chemistry
MH  - Soil Pollutants/*chemistry
MH  - Spectrometry, Mass, Electrospray Ionization/methods
MH  - Tandem Mass Spectrometry/*methods
MH  - Triazoles/*chemistry
EDAT- 2014/10/04 06:00
MHDA- 2014/10/29 06:00
CRDT- 2014/10/04 06:00
PHST- 2014/10/04 06:00 [entrez]
PHST- 2014/10/04 06:00 [pubmed]
PHST- 2014/10/29 06:00 [medline]
PST - ppublish
SO  - Zhongguo Zhong Yao Za Zhi. 2014 Jul;39(13):2464-8.