PMID- 25277757
OWN - NLM
STAT- MEDLINE
DCOM- 20161216
LR  - 20161217
IS  - 1751-7893 (Electronic)
IS  - 1751-7885 (Linking)
VI  - 10
IP  - 2
DP  - 2016 Apr
TI  - Examination of the Positive and Negative Syndrome Scale factor structure and 
      longitudinal relationships with functioning in early psychosis.
PG  - 165-70
LID - 10.1111/eip.12190 [doi]
AB  - AIM: We examined the factor structure of the Positive and Negative Syndrome Scale 
      (PANSS) in early-episode psychosis and its relationships with functioning at 
      baseline and follow-up. METHODS: A total of 240 consecutive admissions to an 
      early intervention in psychosis clinic were assessed at intake to the program 
      with the PANSS, Global Assessment of Functioning (GAF) and Social and 
      Occupational Functioning Assessment Scale (SOFAS). Seventy individuals were 
      reassessed at follow-up. A maximum likelihood factor analysis was conducted on 
      baseline PANSS scores and the ability of each factor to predict baseline and 
      follow-up GAF and SOFAS was examined. RESULTS: A five-factor model with varimax 
      rotation was the best fit to our data and was largely congruent with factors 
      found previously. The negative symptom factor was the best predictor of GAF and 
      SOFAS at baseline and follow-up. CONCLUSION: Negative symptoms are the best 
      symptomatic predictor of functioning in individuals with early psychosis and are 
      an important treatment target to improve recovery.
CI  - (c) 2014 Wiley Publishing Asia Pty Ltd.
FAU - Best, Michael W
AU  - Best MW
AD  - Department of Psychology, Queen's University, Kingston, Ontario, Canada.
FAU - Grossman, Michael
AU  - Grossman M
AD  - Department of Psychology, Queen's University, Kingston, Ontario, Canada.
FAU - Oyewumi, L Kola
AU  - Oyewumi LK
AD  - Department of Psychiatry, Queen's University, Kingston, Ontario, Canada.
AD  - Centre for Neuroscience Studies, Queen's University, Kingston, Ontario, Canada.
FAU - Bowie, Christopher R
AU  - Bowie CR
AD  - Department of Psychology, Queen's University, Kingston, Ontario, Canada.
AD  - Department of Psychiatry, Queen's University, Kingston, Ontario, Canada.
AD  - Centre for Neuroscience Studies, Queen's University, Kingston, Ontario, Canada.
LA  - eng
PT  - Journal Article
DEP - 20141002
PL  - Australia
TA  - Early Interv Psychiatry
JT  - Early intervention in psychiatry
JID - 101320027
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Early Diagnosis
MH  - Factor Analysis, Statistical
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Predictive Value of Tests
MH  - *Psychiatric Status Rating Scales
MH  - Psychotic Disorders/*diagnosis
MH  - Young Adult
OTO - NOTNLM
OT  - early psychosis intervention
OT  - factor analysis
OT  - psychotic disorder
OT  - schizophrenia
OT  - symptom
EDAT- 2014/10/04 06:00
MHDA- 2016/12/17 06:00
CRDT- 2014/10/04 06:00
PHST- 2014/04/14 00:00 [received]
PHST- 2014/08/19 00:00 [accepted]
PHST- 2014/10/04 06:00 [entrez]
PHST- 2014/10/04 06:00 [pubmed]
PHST- 2016/12/17 06:00 [medline]
AID - 10.1111/eip.12190 [doi]
PST - ppublish
SO  - Early Interv Psychiatry. 2016 Apr;10(2):165-70. doi: 10.1111/eip.12190. Epub 2014 
      Oct 2.