PMID- 25281622
OWN - NLM
STAT- MEDLINE
DCOM- 20150616
LR  - 20141004
IS  - 0974-5181 (Electronic)
IS  - 0971-9784 (Linking)
VI  - 17
IP  - 4
DP  - 2014 Oct-Dec
TI  - Comparison between continuous non-invasive estimated cardiac output by pulse wave 
      transit time and thermodilution method.
PG  - 273-7
LID - 10.4103/0971-9784.142059 [doi]
AB  - AIMS AND OBJECTIVES: Cardiac output (CO) measurement is essential for many 
      therapeutic decisions in anesthesia and critical care. Most available 
      non-invasive CO measuring methods have an invasive component. We investigate 
      "pulse wave transit time" (estimated continuous cardiac output [esCCO]) a method 
      of CO measurement that has no invasive component to its use. MATERIALS AND 
      METHODS: After institutional ethical committee approval, 14 adult (21-85 years) 
      patients undergoing surgery and requiring pulmonary artery catheter (PAC) for 
      measuring CO, were included. Postoperatively CO readings were taken 
      simultaneously with thermodilution (TD) via PAC and esCCO, whenever a change in 
      CO was expected due to therapeutic interventions. Both monitoring methods were 
      continued until patients' discharge from the Intensive Care Unit and observer 
      recording values using TD method was blinded to values measured by esCCO system. 
      RESULTS: Three hundred and one readings were obtained simultaneously from both 
      methods. Correlation and concordance between the two methods was derived using 
      Bland-Altman analysis. Measured values showed significant correlation between 
      esCCO and TD ( r = 0.6, P < 0.001, 95% confidence limits of 0.51-0.68). Mean and 
      (standard deviation) for bias and precision were 0.13 (2.27) L/min and 6.56 
      (2.19) L/min, respectively. The 95% confidence interval for bias was - 4.32 to 
      4.58 L/min and for precision 2.27 to10.85 L/min. CONCLUSIONS: Although, esCCO is 
      the only true non-invasive continuous CO monitor available and even though its 
      values change proportionately to TD method (gold standard) with the present 
      degree of error its utility for clinical/therapeutic decision-making is 
      questionable.
FAU - Sinha, Ashish C
AU  - Sinha AC
AD  - Department of Anaesthesia, Drexel University College of Medicine, Philadelphia, 
      PA, USA.
FAU - Singh, Preet Mohinder
AU  - Singh PM
FAU - Grewal, Navneet
AU  - Grewal N
FAU - Aman, Mansoor
AU  - Aman M
FAU - Dubowitz, Gerald
AU  - Dubowitz G
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - India
TA  - Ann Card Anaesth
JT  - Annals of cardiac anaesthesia
JID - 9815987
SB  - IM
CIN - Ann Card Anaesth. 2014 Oct-Dec;17(4):278. PMID: 25281623
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Cardiac Output/*physiology
MH  - Catheterization, Swan-Ganz/methods
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Monitoring, Intraoperative/methods/statistics & numerical data
MH  - Monitoring, Physiologic/*methods/*statistics & numerical data
MH  - Prospective Studies
MH  - Pulse Wave Analysis/*methods/*statistics & numerical data
MH  - Reproducibility of Results
MH  - Thermodilution/methods/statistics & numerical data
MH  - Young Adult
EDAT- 2014/10/05 06:00
MHDA- 2015/06/17 06:00
CRDT- 2014/10/05 06:00
PHST- 2014/10/05 06:00 [entrez]
PHST- 2014/10/05 06:00 [pubmed]
PHST- 2015/06/17 06:00 [medline]
AID - AnnCardAnaesth_2014_17_4_273_142059 [pii]
AID - 10.4103/0971-9784.142059 [doi]
PST - ppublish
SO  - Ann Card Anaesth. 2014 Oct-Dec;17(4):273-7. doi: 10.4103/0971-9784.142059.