PMID- 25282824
OWN - NLM
STAT- MEDLINE
DCOM- 20141017
LR  - 20171116
IS  - 1026-3543 (Print)
IS  - 1026-3543 (Linking)
VI  - 145
IP  - 2
DP  - 2014
TI  - [Characteristics of the spermatogenic epithelium in the testis of newborn 
      rats--the offspring of female rats with chronic liver injury of various genesis].
PG  - 42-5
AB  - The effect of chronic injury of hepatobiliary system of various genesis in 
      females rats on the formation of spermatogenic epithelium in the testis of their 
      newborn offspring was studied. The models of toxic (CCl4) and medicinal 
      (tetracycline, paracetamol) liver injury were used. The state of the seminiferous 
      epithelium was assessed on the serial histological sections of the testis with 
      the use of the morphometric device. In experimental animals, a reduction of the 
      diameter and the area of the seminiferous tubules (ST) was detected, associated 
      with the decline of the total number of spermatogenic cells, spermatogonia of 
      various generations, total number of spermatocytes and Sertoli cells. At the same 
      time, in the newborn rats of all the experimental groups, the number of ST with 
      the desquamated epithelium, and that one of the multinucleated spermatogenic 
      cells with fragmented and pyknotic nuclei were increased.
FAU - Sizonenko, M L
AU  - Sizonenko ML
FAU - Briukhin, G V
AU  - Briukhin GV
LA  - rus
PT  - Journal Article
PL  - Russia (Federation)
TA  - Morfologiia
JT  - Morfologiia (Saint Petersburg, Russia)
JID - 9317610
SB  - IM
MH  - Animals
MH  - Animals, Newborn
MH  - *Chemical and Drug Induced Liver Injury, Chronic/metabolism/pathology
MH  - Female
MH  - *Liver
MH  - Male
MH  - Pregnancy
MH  - *Prenatal Exposure Delayed Effects/metabolism/pathology
MH  - Rats
MH  - Rats, Wistar
MH  - *Seminiferous Epithelium/metabolism/pathology
MH  - *Spermatogonia/metabolism/pathology
EDAT- 2014/10/07 06:00
MHDA- 2014/10/18 06:00
CRDT- 2014/10/07 06:00
PHST- 2014/10/07 06:00 [entrez]
PHST- 2014/10/07 06:00 [pubmed]
PHST- 2014/10/18 06:00 [medline]
PST - ppublish
SO  - Morfologiia. 2014;145(2):42-5.