PMID- 25286779
OWN - NLM
STAT- MEDLINE
DCOM- 20150615
LR  - 20151119
IS  - 1875-6263 (Electronic)
IS  - 1028-4559 (Linking)
VI  - 53
IP  - 3
DP  - 2014 Sep
TI  - Primary fallopian tube cancer: domestic data and up-to-date review.
PG  - 287-92
LID - S1028-4559(14)00118-1 [pii]
LID - 10.1016/j.tjog.2014.07.003 [doi]
AB  - Primary fallopian tube carcinoma (PFTC) is a rare gynecological malignancy with 
      the following characteristics: its preoperative diagnosis is easy to miss or 
      delay because of a lack of specific symptoms and signs; it is difficult to 
      distinguish from serous epithelial ovarian cancer or primary peritoneal serous 
      carcinoma during or even after operation because they have the same 
      histopathological features; and there is uncertainty regarding the optimal 
      management because of the lack of available standard guidelines. All of these 
      factors contribute to the major challenge of undertaking a comprehensive study of 
      this disease. To improve our understanding of this rare disease, the domestic 
      data were summarized first. We searched PubMed on this topic, using the term 
      "primary fallopian tube tumor and Taiwan" (from January 1, 1990 to November 3, 
      2013) and identified 15 published articles, but only 11 studies focused on the 
      outcome of patients with PFTC in Taiwan. These limited data were not enough to 
      increase our knowledge in dealing with this disease; therefore, the addition of 
      large series or published review articles addressing this topic was needed. 
      According to these reports, we concluded: (1) the main type of PFTC was serous 
      type, often poorly differentiated; (2) the diagnosis of PFTC is frequently missed 
      or delayed; (3) PFTC is often of an earlier International Federation of 
      Gynecology and Obstetrics (FIGO) stage than is epithelial ovarian cancer (EOC), 
      because of the appearance of earlier but nonspecific symptoms or signs, such as 
      abdominal pain, vaginal bleeding, and watery discharge or mass; (4) the most 
      important clinicopathological prognostic factor was FIGO stage; (5) the 
      therapeutic strategy is still uncertain, but is often based on the guidelines for 
      treating EOC. An intensive surgical effort such as a complete surgical resection 
      or optimal cytoreduction surgery with a minimal residual tumor followed by a 
      platinum-paclitaxel combination chemotherapy with/without targeted therapy (for 
      example, antiangiogenesis agents) may provide the best possibility of 
      disease-free or overall survival.
CI  - Copyright (c) 2014. Published by Elsevier B.V.
FAU - Horng, Huann-Cheng
AU  - Horng HC
AD  - Division of Gynecology, Department of Obstetrics and Gynecology, Taipei Veterans 
      General Hospital, Taipei, Taiwan; Department of Obstetrics and Gynecology, 
      National Yang-Ming University School of Medicine, Taipei, Taiwan.
FAU - Teng, Sen-Wen
AU  - Teng SW
AD  - Department of Obstetrics and Gynecology, Cardinal Tien Hospital-Hsintien, New 
      Taipei City, Taiwan; Department of Obstetrics and Gynecology, Fu Jen Catholic 
      University, New Taipei City, Taiwan.
FAU - Huang, Ben-Shian
AU  - Huang BS
AD  - Department of Obstetrics and Gynecology, National Yang-Ming University School of 
      Medicine, Taipei, Taiwan; Department of Obstetrics and Gynecology, National 
      Yang-Ming University Hospital, Ilan, Taiwan.
FAU - Sun, Hsu-Dong
AU  - Sun HD
AD  - Department of Obstetrics and Gynecology, National Yang-Ming University School of 
      Medicine, Taipei, Taiwan; Department of Obstetrics and Gynecology, Far Eastern 
      Memorial Hospital, New Taipei City, Taiwan.
FAU - Yen, Ming-Shyen
AU  - Yen MS
AD  - Division of Gynecology, Department of Obstetrics and Gynecology, Taipei Veterans 
      General Hospital, Taipei, Taiwan; Department of Obstetrics and Gynecology, 
      National Yang-Ming University School of Medicine, Taipei, Taiwan. Electronic 
      address: msyen@vghtpe.gov.tw.
FAU - Wang, Peng-Hui
AU  - Wang PH
AD  - Division of Gynecology, Department of Obstetrics and Gynecology, Taipei Veterans 
      General Hospital, Taipei, Taiwan; Department of Obstetrics and Gynecology, 
      National Yang-Ming University School of Medicine, Taipei, Taiwan; Department of 
      Medical Research, China Medical University Hospital, Taichung, Taiwan; Infection 
      and Immunity Research, National Yang-Ming University, Taipei, Taiwan; Immunology 
      Center, Taipei Veterans General Hospital, Taipei, Taiwan. Electronic address: 
      phwang@vghtpe.gov.tw.
FAU - Tsui, Kuan-Hao
AU  - Tsui KH
AD  - Division of Gynecology, Department of Obstetrics and Gynecology, Taipei Veterans 
      General Hospital, Taipei, Taiwan; Department of Biological Science, National Sun 
      Yat-Sen University, Kaohsiung, Taiwan; Department of Obstetrics and Gynecology, 
      Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan; Department of Pharmacy 
      and Graduate Institute of Pharmaceutical Technology, Tajen University, Pingtung 
      County, Taiwan.
FAU - Wen, Kuo-Chang
AU  - Wen KC
AD  - Division of Gynecology, Department of Obstetrics and Gynecology, Taipei Veterans 
      General Hospital, Taipei, Taiwan; Department of Obstetrics and Gynecology, 
      National Yang-Ming University School of Medicine, Taipei, Taiwan.
FAU - Chen, Yi-Jen
AU  - Chen YJ
AD  - Division of Gynecology, Department of Obstetrics and Gynecology, Taipei Veterans 
      General Hospital, Taipei, Taiwan; Department of Obstetrics and Gynecology, 
      National Yang-Ming University School of Medicine, Taipei, Taiwan.
FAU - Chuang, Chi-Mu
AU  - Chuang CM
AD  - Division of Gynecology, Department of Obstetrics and Gynecology, Taipei Veterans 
      General Hospital, Taipei, Taiwan; Department of Obstetrics and Gynecology, 
      National Yang-Ming University School of Medicine, Taipei, Taiwan.
FAU - Chao, Hsiang-Tai
AU  - Chao HT
AD  - Division of Gynecology, Department of Obstetrics and Gynecology, Taipei Veterans 
      General Hospital, Taipei, Taiwan; Department of Obstetrics and Gynecology, 
      National Yang-Ming University School of Medicine, Taipei, Taiwan.
FAU - Chang, Wen-Hsun
AU  - Chang WH
AD  - Department of Nursing, Taipei Veterans General Hospital, Taipei, Taiwan; 
      Department of Nursing, National Yang-Ming University School of Nursing, Taipei, 
      Taiwan.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
PL  - China (Republic : 1949- )
TA  - Taiwan J Obstet Gynecol
JT  - Taiwanese journal of obstetrics & gynecology
JID - 101213819
RN  - 0 (Biomarkers, Tumor)
RN  - 0 (CA-125 Antigen)
SB  - IM
MH  - Abdominal Pain/etiology
MH  - Asymptomatic Diseases
MH  - Biomarkers, Tumor/blood
MH  - CA-125 Antigen/blood
MH  - Carcinoma/blood/diagnosis/therapy
MH  - Chemotherapy, Adjuvant
MH  - Diagnostic Imaging
MH  - Fallopian Tube Neoplasms/blood/*diagnosis/*therapy
MH  - Female
MH  - Humans
MH  - Lymph Node Excision
MH  - Neoplasm Staging
MH  - Salpingectomy
MH  - Uterine Hemorrhage/etiology
MH  - Vaginal Smears
OTO - NOTNLM
OT  - outcome
OT  - primary fallopian tube carcinoma
OT  - prognosis
OT  - treatment
EDAT- 2014/10/08 06:00
MHDA- 2015/06/16 06:00
CRDT- 2014/10/08 06:00
PHST- 2014/04/21 00:00 [accepted]
PHST- 2014/10/08 06:00 [entrez]
PHST- 2014/10/08 06:00 [pubmed]
PHST- 2015/06/16 06:00 [medline]
AID - S1028-4559(14)00118-1 [pii]
AID - 10.1016/j.tjog.2014.07.003 [doi]
PST - ppublish
SO  - Taiwan J Obstet Gynecol. 2014 Sep;53(3):287-92. doi: 10.1016/j.tjog.2014.07.003.