PMID- 25289111 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20211021 IS - 1792-1074 (Print) IS - 1792-1082 (Electronic) IS - 1792-1074 (Linking) VI - 8 IP - 5 DP - 2014 Nov TI - ANXA9 gene expression in colorectal cancer: A novel marker for prognosis. PG - 2313-2317 AB - Annexin A9 (ANXA9) is involved with the interaction with membrane phospholipids in a Ca(2+)-dependent manner. A previous study has shown that ANXA9 expression is associated with bone metastasis in breast cancer, whereas its significance in colorectal cancer (CRC) is unknown. The present study was comprised of 100 patients who underwent surgery for CRC. The correlation between gene expression and the clinical parameters of the patients was assessed. Patients with high ANXA9 expression were statistically susceptible to a relatively worse prognosis, and those with low ANXA9 expression showed improved overall survival compared with those with high expression. In conclusion, the present data suggests that ANXA9 expression is a prognostic factor in CRC patients. FAU - Miyoshi, Norikatsu AU - Miyoshi N AD - Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Osaka 537-8511, Japan. FAU - Yamamoto, Hirofumi AU - Yamamoto H AD - Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Suita, Osaka 565-0871, Japan. FAU - Mimori, Koshi AU - Mimori K AD - Department of Molecular and Cellular Biology, Division of Molecular and Surgical Oncology, Medical Institute of Bioregulation, Kyushu University, Beppu, Ohita 874-0838, Japan. FAU - Yamashita, Shinya AU - Yamashita S AD - Department of Surgery, National Hospital Organization Kure Medical Center, Kure, Hiroshima 737-0023, Japan. FAU - Miyazaki, Susumu AU - Miyazaki S AD - Department of Surgery, Osaka General Medical Center, Osaka, Osaka 558-8558, Japan. FAU - Nakagawa, Sumiko AU - Nakagawa S AD - Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Suita, Osaka 565-0871, Japan. FAU - Ishii, Hideshi AU - Ishii H AD - Department of Frontier Science for Cancer and Chemotherapy, Osaka University, Suita, Osaka 565-0871, Japan. FAU - Noura, Shingo AU - Noura S AD - Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Osaka 537-8511, Japan. FAU - Ohue, Masayuki AU - Ohue M AD - Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Osaka 537-8511, Japan. FAU - Yano, Masahiko AU - Yano M AD - Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Osaka 537-8511, Japan. FAU - Doki, Yuichiro AU - Doki Y AD - Department of Surgery, National Hospital Organization Kure Medical Center, Kure, Hiroshima 737-0023, Japan. FAU - Mori, Masaki AU - Mori M AD - Department of Surgery, National Hospital Organization Kure Medical Center, Kure, Hiroshima 737-0023, Japan. LA - eng PT - Journal Article DEP - 20140825 PL - Greece TA - Oncol Lett JT - Oncology letters JID - 101531236 PMC - PMC4186559 OTO - NOTNLM OT - ANXA9 OT - colorectal cancer OT - prognosis EDAT- 2014/10/08 06:00 MHDA- 2014/10/08 06:01 PMCR- 2014/08/25 CRDT- 2014/10/08 06:00 PHST- 2014/02/19 00:00 [received] PHST- 2014/08/01 00:00 [accepted] PHST- 2014/10/08 06:00 [entrez] PHST- 2014/10/08 06:00 [pubmed] PHST- 2014/10/08 06:01 [medline] PHST- 2014/08/25 00:00 [pmc-release] AID - ol-08-05-2313 [pii] AID - 10.3892/ol.2014.2477 [doi] PST - ppublish SO - Oncol Lett. 2014 Nov;8(5):2313-2317. doi: 10.3892/ol.2014.2477. Epub 2014 Aug 25.