PMID- 25293803
OWN - NLM
STAT- MEDLINE
DCOM- 20160419
LR  - 20211021
IS  - 1746-6148 (Electronic)
IS  - 1746-6148 (Linking)
VI  - 10
DP  - 2014 Oct 8
TI  - Prescribing practices of primary-care veterinary practitioners in dogs diagnosed 
      with bacterial pyoderma.
PG  - 240
LID - 10.1186/s12917-014-0240-5 [doi]
LID - 240
AB  - BACKGROUND: Concern has been raised regarding the potential contributions of 
      veterinary antimicrobial use to increasing levels of resistance in bacteria 
      critically important to human health. Canine pyoderma is a frequent, often 
      recurrent diagnosis in pet dogs, usually attributable to secondary bacterial 
      infection of the skin. Lesions can range in severity based on the location, total 
      area and depth of tissue affected and antimicrobial therapy is recommended for 
      resolution. This study aimed to describe patient signalment, disease 
      characteristics and treatment prescribed in a large number of UK, primary-care 
      canine pyoderma cases and to estimate pyoderma prevalence in the UK vet-visiting 
      canine population. RESULTS: Of 54,600 dogs presented to 73 participating 
      practices in 2010, 683 (1.3%) had a pyoderma diagnosis recorded in available 
      electronic patient record (EPR) data. Antimicrobials were dispensed in 97% of 
      cases and most dogs were prescribed systemic therapy (92%). Agents most 
      frequently prescribed were amoxicillin-clavulanate, cefalexin, clindamycin and 
      cefovecin. Systemic antimicrobials were prescribed for fewer than 14 days in 
      around 40% of study cases reviewed in detail. Prescribed daily doses were below 
      minimum recommended daily dose (MRDD) in 26% of 43 dogs with sufficient 
      information for calculation of minimum dose. CONCLUSIONS: Antimicrobial 
      prescribing behaviour for treatment of canine pyoderma was variable but 
      frequently appeared inconsistent with current recommendations. Use of clinical 
      data from primary practice EPRs can provide valuable insight into common clinical 
      conditions and associated prescribing.
FAU - Summers, Jennifer F
AU  - Summers JF
AD  - Department of Population and Public Health (PPH), Royal Veterinary College, 
      Hatfield, UK. jsummers@rvc.ac.uk.
FAU - Hendricks, Anke
AU  - Hendricks A
AD  - Queen Mother Hospital for Animals (QMHA), Royal Veterinary College, Hatfield, UK. 
      ahendricks@rvc.ac.uk.
FAU - Brodbelt, David C
AU  - Brodbelt DC
AD  - Department of Population and Public Health (PPH), Royal Veterinary College, 
      Hatfield, UK. dbrodbelt@rvc.ac.uk.
LA  - eng
GR  - Biotechnology and Biological Sciences Research Council/United Kingdom
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20141008
PL  - England
TA  - BMC Vet Res
JT  - BMC veterinary research
JID - 101249759
RN  - 0 (Anti-Bacterial Agents)
SB  - IM
MH  - Administration, Oral
MH  - Administration, Topical
MH  - Animals
MH  - Anti-Bacterial Agents/administration & dosage/therapeutic use
MH  - Dog Diseases/*drug therapy
MH  - Dogs
MH  - Female
MH  - Male
MH  - Pyoderma/diagnosis/drug therapy/epidemiology/*veterinary
MH  - United Kingdom/epidemiology
MH  - Veterinarians/*statistics & numerical data
PMC - PMC4193143
EDAT- 2014/10/09 06:00
MHDA- 2016/04/20 06:00
PMCR- 2014/10/08
CRDT- 2014/10/09 06:00
PHST- 2014/06/25 00:00 [received]
PHST- 2014/09/23 00:00 [accepted]
PHST- 2014/10/09 06:00 [entrez]
PHST- 2014/10/09 06:00 [pubmed]
PHST- 2016/04/20 06:00 [medline]
PHST- 2014/10/08 00:00 [pmc-release]
AID - s12917-014-0240-5 [pii]
AID - 240 [pii]
AID - 10.1186/s12917-014-0240-5 [doi]
PST - epublish
SO  - BMC Vet Res. 2014 Oct 8;10:240. doi: 10.1186/s12917-014-0240-5.