PMID- 25297095
OWN - NLM
STAT- MEDLINE
DCOM- 20150708
LR  - 20211021
IS  - 1529-2401 (Electronic)
IS  - 0270-6474 (Print)
IS  - 0270-6474 (Linking)
VI  - 34
IP  - 41
DP  - 2014 Oct 8
TI  - The fusion of mental imagery and sensation in the temporal association cortex.
PG  - 13684-92
LID - 10.1523/JNEUROSCI.0943-14.2014 [doi]
AB  - It is well understood that the brain integrates information that is provided to 
      our different senses to generate a coherent multisensory percept of the world 
      around us (Stein and Stanford, 2008), but how does the brain handle concurrent 
      sensory information from our mind and the external world? Recent behavioral 
      experiments have found that mental imagery--the internal representation of 
      sensory stimuli in one's mind--can also lead to integrated multisensory 
      perception (Berger and Ehrsson, 2013); however, the neural mechanisms of this 
      process have not yet been explored. Here, using functional magnetic resonance 
      imaging and an adapted version of a well known multisensory illusion (i.e., the 
      ventriloquist illusion; Howard and Templeton, 1966), we investigated the neural 
      basis of mental imagery-induced multisensory perception in humans. We found that 
      simultaneous visual mental imagery and auditory stimulation led to an illusory 
      translocation of auditory stimuli and was associated with increased activity in 
      the left superior temporal sulcus (L. STS), a key site for the integration of 
      real audiovisual stimuli (Beauchamp et al., 2004a, 2010; Driver and Noesselt, 
      2008; Ghazanfar et al., 2008; Dahl et al., 2009). This imagery-induced 
      ventriloquist illusion was also associated with increased effective connectivity 
      between the L. STS and the auditory cortex. These findings suggest an important 
      role of the temporal association cortex in integrating imagined visual stimuli 
      with real auditory stimuli, and further suggest that connectivity between the STS 
      and auditory cortex plays a modulatory role in spatially localizing auditory 
      stimuli in the presence of imagined visual stimuli.
CI  - Copyright (c) 2014 the authors 0270-6474/14/3313684-09$15.00/0.
FAU - Berger, Christopher C
AU  - Berger CC
AD  - Department of Neuroscience, Karolinska Institutet, 171 77 Stockholm, Sweden 
      christopher.c.berger@ki.se.
FAU - Ehrsson, H Henrik
AU  - Ehrsson HH
AD  - Department of Neuroscience, Karolinska Institutet, 171 77 Stockholm, Sweden.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - J Neurosci
JT  - The Journal of neuroscience : the official journal of the Society for 
      Neuroscience
JID - 8102140
SB  - IM
MH  - Acoustic Stimulation
MH  - Adult
MH  - Auditory Cortex/physiology
MH  - Female
MH  - Humans
MH  - Illusions/physiology
MH  - Imagination/*physiology
MH  - Male
MH  - Neural Pathways/cytology/physiology
MH  - Photic Stimulation
MH  - Sensation/*physiology
MH  - Sound Localization/physiology
MH  - Temporal Lobe/*physiology
MH  - Visual Perception/physiology
PMC - PMC4188966
OTO - NOTNLM
OT  - auditory cortex
OT  - mental imagery
OT  - multisensory
OT  - superior temporal sulcus
OT  - ventriloquism
EDAT- 2014/10/10 06:00
MHDA- 2015/07/15 06:00
PMCR- 2014/10/08
CRDT- 2014/10/10 06:00
PHST- 2014/10/10 06:00 [entrez]
PHST- 2014/10/10 06:00 [pubmed]
PHST- 2015/07/15 06:00 [medline]
PHST- 2014/10/08 00:00 [pmc-release]
AID - 34/41/13684 [pii]
AID - 0943-14 [pii]
AID - 10.1523/JNEUROSCI.0943-14.2014 [doi]
PST - ppublish
SO  - J Neurosci. 2014 Oct 8;34(41):13684-92. doi: 10.1523/JNEUROSCI.0943-14.2014.